TOKYO, Apr 25, 2025 - (JCN Newswire via SeaPRwire.com) - DENSO, a leading mobility supplier, today announced global financial results for its 2025 fiscal year, ending March 31, 2025:Consolidated revenue totaled 7,161.8 billion yen (US$47.9 billion), a 0.2 percent increase from the previous year.Consolidated operating profit totaled 519.0 billion yen (US$3.5 billion), a 36.4 percent increase from the previous year.Consolidated profit attributable to owners of the parent company totaled 419.1 billion yen(US$2.8 billion), a 34.0 percent increase from the previous year.“Despite lower vehicle production volumes in Asia and suspensions of operations by Japanese customers, revenue increased compared to the previous year thanks in part to yen depreciation, which boosted our performance overall. Operating profit increased compared to the previous year as well through foreign exchange gains and cost management efforts, helping us overcome lower production volumes and increasing parts and material costs.” said Yasushi Matsui, CFO, Executive Vice President and member of the Board of Directors of DENSO CORPORATION. “In the next fiscal year, we forecast revenue to slightly decrease to 7,050.0 billion yen (US$47.2 billion), reflecting conversion differences caused by the precondition of a stronger yen. We forecast operating profit, however, to rise to 675.0 billion yen (US$4.5 billion) and operating profit margin to be 9.6%. To reach these targets, we will continue to manage increasing parts costs and foreign exchange losses, and leverage business improvement activities to exceed potential market challenges. The annual dividend for the concluded fiscal year is 64 yen, with DOE up to 3.5%. The forecast for the next fiscal year is 64 yen, same as the 2025 fiscal year. We continue to strive to improve the DOE level in a long-term and stable manner.”In Japan, revenue increased to 4,216.4 billion yen (US$28.2 billion), up 1.2% from the previous year, and operating profit increased to 220.5 billion yen (US$1,475.4 million), up 158.9% from the previous year.In North America, revenue increased to 1,863.2 billion yen (US$12.5 billion), up 5.4% from the previous year, and operating profit increased to 98.1 billion yen (US$656.0 million), up 79.8% from the previous year.In Europe, revenue decreased to 718.7 billion yen (US$4.8 billion), down 8.0% from the previous year, and operating profit decreased to 8.7 billion yen (US$57.9 million), down 72.1% from the previous year.In Asia, revenue decreased to 1,940.1 billion yen (US$13.0 billion), down 2.3% from the previous year and operating profit decreased to 169.5 billion yen (US$1,133.7 million), down 8.1% from the previous year.In other areas, revenue increased to 119.0 billion yen (US$0.8 billion), up 3.3% from the previous year, and operating profit decreased to 22.3 billion yen (US$149.0 million), down 10.1% from the previous year.Forecast for Fiscal Year Ending March 31, 2026Revenue 7,050.0 billion yen[US$47.2 billion] -111.8 billion yen(-1.6 percent) Operating profit 675.0 billion yen[US$4.5 billion] +156.0 billion yen(+30.1 percent) Profit before profit taxes 743.0 billion yen[US$5.0 billion] +165.0 billion yen(+28.5 percent) Profit attributable to owners of the parent company 515.0 billion yen[US$3.4 billion] +95.9 billion yen(+22.9 percent) ROE 10.6% +2.6%pt(Notes)The above forecasts are created based on information obtained by the date of this announcement and the actual results may differ due to various causes in the future. U.S. dollar amounts have been translated, for convenience only, at the rate of 149.48yen = US$1, the approximate exchange rate prevailing in the Tokyo Foreign Exchange Market on March 31, 2025. Like in the U.S. billion is used in the sense of one thousand million. Foreign exchange rates of the Forecast for Fiscal Year Ending March 31, 2026, as a precondition are US$=145.0yen, Euro=160.0yen, CNY=20.0yen.About DENSO CORPORATIONGlobally headquartered in Kariya, Japan, DENSO is a $47.9 billion leading mobility supplier that develops advanced technology and components for nearly every vehicle make and model on the road today. With manufacturing at its core, DENSO invests in around 180 facilities worldwide to provide opportunities for rewarding careers and to produce cutting-edge electrification, powertrain, thermal and mobility electronics products, among others, that change how the world moves. In developing such solutions, the company’s 158,000 global employees are paving the way to a mobility future that improves lives, eliminates traffic accidents, and preserves the environment. DENSO spent around 8.6 percent of its global consolidated sales on research and development in the fiscal year ending March 31, 2025. For more information about DENSO’s operations worldwide, visit https://www.denso.com/global. Copyright 2025 JCN Newswire via SeaPRwire.com.
เดือน: เมษายน 2025
DENSO and DELPHY Sign Memorandum of Understanding to Develop Data-Driven Smart Horticulture
KARIYA, JAPAN, Apr 24, 2025 - (JCN Newswire via SeaPRwire.com) - DENSO CORPORATION and DELPHY GROEP BV have signed a Memorandum of Understanding (MOU) aimed at developing and promoting data-driven smart horticulture(1).From left: DELPHY GROEP BV Managing Partner Horticulture Aad van den Berg,DENSO CORPORATION Food Value Chain Business Development Division Executive Officer Yasushi MukaiRecently, the instability of agricultural production caused by factors such as climate change and the decline in the farming population, as well as the resulting food shortages has become pressing issues. Under these circumstances, there is a global need to enable anyone a stable, sustainable agricultural production, anytime, in any environment.DENSO has been engaged in the horticultural business by leveraging technology developed in the automotive sector. By developing environmental control systems and greenhouses for horticulture, as well as harvest robots(2), DENSO has continuously enhanced its sensing capabilities in greenhouse IoT and harvesting processes.DELPHY is a leading cultivation consulting company, staffed by numerous experts with extensive, long-term experience in cultivation support. The cultivation management software QMS(3) provided by DELPHY inputs climate data such as temperature and sunlight, along with crop data including fruit counts and weights, into a mathematical plant growth model. By using these data to plan cultivation, DELPHY has been assisting producers in achieving stable, long-term cultivation.By drawing on their respective strengths, DENSO and DELPHY have signed the MOU to begin exploring data-driven smart horticulture, which optimizes the cultivation environment and methods by consolidating and utilizing data essential for crop growth. The main initiatives are as follows:■ System Development to Achieve Stable Planned CultivationBy automatically collecting crop data—which growers have until now observed visually or measured by hand—through DENSO’s sensing technology, accuracy is enhanced. Furthermore, by entering this crop data into DELPHY ’s QMS, it becomes possible to improve the precision of cultivation planning. Subsequently, by leveraging that cultivation plan to control the greenhouse environment and provide instructions to workers or automated equipment, stable and planned cultivation can be achieved. The two companies will explore the development of a series of systems to realize this stable, planned cultivation.■ System Development for Cultivation Simulation under a Digital Twin(4) EnvironmentBy using DENSO’s digital twin technology, it becomes possible to recreate in three-dimensional data the plant structure that would result from cultivating based on the cultivation plan devised by DELPHY’s QMS. This enables analysis and prediction of crop growth in a digital twin environment even before actual cultivation takes place. Both companies will explore the development of a series of systems to realize these cultivation simulations.Based on the MOU, DENSO and DELPHY aim to interlink these two systems to realize data-driven smart horticulture by 2030. Together, the two companies will accelerate initiatives worldwide to achieve stable and sustainable agriculture.DENSO CORPORATIONFood Value Chain Business Development DivisionExecutive OfficerYasushi MukaiThrough our collaboration with DELPHY, we have taken a new step toward realizing innovative cultivation solutions that enable planned production by integrating our sensing and digital technologies with DELPHY’s cultivation know-how. We will continue to challenge ourselves to deliver safe and reliable food anytime, anywhere, and for everyone.DELPHY GROEP BVManaging Partner HorticultureAad van den BergThe road to autonomous crop cultivation requires new technologies for horticulture. On this road to economically sustainable horticulture, technologies from the automotive industry will make a major contribution. By integrating DENSO technologies with DELPHY's QMS Cultivation Management software, we can continue to contribute to this development. We make Growers better!*1Data-driven smart horticulture is a method of collecting horticultural data using sensors and IoT devices and optimizing the cultivation process through AI and big data analysis.*2 Please refer to the following URL for past announcements regarding the fully automated harvest robot Artemy®.https://www.denso.com/global/en/news/newsroom/2024/20240513-g01/*3 Please refer to the following URL for more information about the QMS.https://delphy.nl/en/services/data-driven-crop-management/*4 A Digital Twin is a technology that involves creating a “twin” within a digital virtual space using data gathered from the real world, enabling a wide range of simulations.About DENSO CORPORATIONDENSO is a global automotive parts manufacturer that provides advanced automotive technologies, systems, and products. Leveraging the core technologies it has developed through its experience in automotive components, DENSO is expanding the scope of its value offerings to include factory automation, food distribution, agriculture (Ag Tech), and more. Among these, in order to deliver safe and reliable food—essential to people’s daily lives—DENSO positions agriculture as an important business domain. Through automated harvesting using robots equipped with sensing technologies and through digital-based cultivation environment control, DENSO is working toward the industrialization of farms.https://www.denso.com/global/en/About DELPHY GROEP BVDELPHY is part of Royal Peterson Control Union Group. The Group provides TIC activities and helps businesses navigate complex challenges and drive long-term success in over 80 countries Within the Group DELPHY provides worldwide leading in expertise for food & flowers by knowledge driven services in agriculture and horticulture as research & development, consultancy and projects, dedicated to advancing global food & flower production.https://delphy.nl/ Copyright 2025 JCN Newswire via SeaPRwire.com.
Mooreast Holdings Announces Business Update
SINGAPORE, Apr 25, 2025 - (ACN Newswire via SeaPRwire.com) - The Board of Directors (“Board”) of Mooreast Holdings Ltd. (“Mooreast” or the “Company”), and together with its subsidiaries, the “Group”) wishes to provide an update on several recent developments: Completion of Multi-Buoy Mooring Upgrade Project at Gulf of ThailandFurther to the Company’s announcement dated 12 November 2024, Mooreast wishes to update that the project to upgrade a multi-buoy mooring (“MBM”) system off the eastern shore of the Gulf of Thailand was completed recently. The Group expects to recognise approximately S$8.8 million for this project in the first half of the financial year ending 31 December 2025 (“1H2025”).The successful completion underscores the Group’s capabilities to handle sizeable mooring projects within the oil and gas (“O&G”) industry. Orders related to the O&G sector had been building up in 2H2024, and have continued to gain momentum in the first four months of FY2025. Even with the delivery of the MBM project, current orders at hand are at least equal to those at the end of FY2024. Accordingly, the Group expects revenue in 1H2025 to exceed the S$13.7 million recorded in 1H2024. Additionally, the Group does not expect that the administrative and other operating expenses to increase significantly in FY2025 given that the current staffing is sufficient to support operations and business development in the near term and the absence of fees for professional services rendered to support the Group’s business repositioning efforts in FY2024. Management is actively reviewing and implementing cost control measures to improve overall cost efficiency and profitability moving forward.Update on Floating Wind Energy Projects in Europe and North AsiaOn 1 January 2025, Mr. Eirik Ellingsen (“Mr. Ellingsen”), a Norwegian with deep experience in the offshore and marine sector, was appointed Chief Executive Officer (“CEO”). In the last four months, he has been working closely with Mr. Sim Koon Lam (“Mr Sim”), the founder, Executive Director and Deputy Chairman, on business development strategies amid an increase in commercialisation of floating wind energy projects worldwide.Mr. Ellingsen has been actively engaging players involved in floating wind energy projects in Europe and North Asia, and participated in the WindEurope conference in Copenhagen, Denmark, earlier this month. While the ‘first wave’ of implementation – involving largely demonstration and precommercial projects – had been delayed by the supply chain disruptions caused by the COVID-19 pandemic, the industry has clearly advanced to the ‘second wave’ – commercialisation at scale. With the progress toward commercialisation, the Environmental Resources Management’s “Q3 2024 Global Offshore Wind Market Update" reported over 390 GW of floating wind projects in various planning and development stages. Compared to 50-100 megawatts (“MW”) typical at pre-commercialisation, the latter involves projects of at least 500 MW each. Many of these projects are reaching the final investment decision (“FID”) phase in 2026 and 2027. These include multigigawatt (“GW”) scale projects which can contribute substantially to the growth of offshore wind capacity globally. Typically, mooring and rigging solutions, including anchors, chains, and ropes, account for between 5% to 10% of the total value of each floating wind energy project. Approximately 5.5 GW of floating wind capacity is expected to reach FID in the next 24-36 months. Of this, about two-thirds involve projects in Europe, including those in the North Sea, while a third will come from North Asia. These projects may be deemed as the addressable market of Mooreast. As the Group is currently not targeting U.S. floating wind energy projects, it is not subject to U.S. Government tariffs for its products. Already, Mooreast is working closely with these projects and has indicated its component costings. As these progress to full implementation, developers and partners are looking for a reliable manufacturer capable of handling the large volumes of anchors and mooring components required for these large-scale projects. The Group believes it is uniquely positioned, given its status as Asia’s only ultra-high power anchor designer and manufacturer and its global footprint. Mooreast recently opened new offices in Taiwan and Malaysia in June and July 2024, respectively, expanding its presence in the Asian region.The Group continues to assess the ability of its present facility at 51 Shipyard Road in Singapore to handle production of anchors and components as these projects advance to formal tender, noting that developers have indicated suppliers would need to demonstrate beforehand sufficient capacity to handle the indicative volume. Should such orders escalate beyond the current capacity of the existing yard, Mooreast would need to explore access to additional capacity. Meanwhile, the Company continues to develop its supply chain to better serve its customers globally. The Company will provide updates to shareholders as and when there are material developments regarding floating renewable energy projects. BY ORDER OF THE BOARD MOOREAST HOLDINGS LTD.Mr Eirik Ellingsen Chief Executive Officer23 April 2025This announcement has been reviewed by the Company’s sponsor, UOB Kay Hian Private Limited (the “Sponsor”). This announcement has not been examined or approved by the Singapore Exchange Securities Trading Limited (“SGX-ST”) and the SGX-ST assumes no responsibility for the contents of this announcement, including the correctness of any of the statements or opinions made or reports contained in this announcement. The contact person for the Sponsor is Mr Lance Tan, Senior Vice President, 8 Anthony Road, #01-01, Singapore 229957, telephone (65) 6590 6881. Copyright 2025 ACN Newswire via SeaPRwire.com.
MyJCB App Wins “iF DESIGN AWARD 2025”
TOKYO, Apr 24, 2025 - (JCN Newswire via SeaPRwire.com) - JCB Co., Ltd., Japan's only global payment brand, is proud to announce that MyJCB App, its cardmembers-only mobile app, has won the iF DESIGN AWARD 2025 in the Communication UX category of the User Experience (UX) division. The service design and UI/UX design were developed in collaboration with FOURDIGIT Inc.The iF DESIGN AWARD 2025 recognized the app's excellence in enhancing the user experience through its form, function, and idea, leading to its victory in the Communication UX category of the User Experience (UX) division.Award page: https://ifdesign.com/en/winner-ranking/project/myjcb-app/696672Design Approach Focused on User ExperienceJCB and FOURDIGIT have been collaborating since 2021 to enhance the MyJCB App, encompassing service design, UI/UX design, and the establishment of continuous improvement processes.For the renewal project, they developed a strategy to define the app's role in the service experience, based on a detailed analysis of user behavior and challenges. The team conducted surveys of thousands of users and in-depth interviews with over 50 participants to thoroughly analyze credit card usage patterns and customer needs across various service channels, creating a comprehensive vision for the cross-channel user experience.Following the renewal, the team has continued to improve the app through store comments, user interviews, and usage data analysis, aiming to create an app that serves all customers, regardless of their financial literacy. They remain committed to delivering safer and more convenient card services while actively listening to customer feedback.For more information, please visit: https://www.4digit.com/en/projects/myjcbAbout MyJCB App"MyJCB" is a web service exclusively for JCB cardmembers that offers features, such as viewing transaction history, checking point balance and security alert notifications. Launched in 2016, the MyJCB App underwent a significant renewal in November 2023 under the concept of "card and app integration." The renewal introduced improved visibility and accessibility, along with enhanced security features that reflect JCB's core value of customer safety and security, transforming it into a more convenient and secure app.The app allows users to sort transaction details by amount or date, and includes keyword search functionality for ease of use. Security features include "Card Usage Notifications" and "Security Status Recommendations" that suggest optimal security settings for users, supporting safe card usage.The app continues to evolve with regular updates and new features to meet the diverse needs of all cardmembers, including digital concierge services for THE CLASS and Platinum cardmembers, and customizable app themes with four design options.For more information about the MyJCB App: https://www.jcb.co.jp/myjcb/app/index.htmlFor details about the Digital Concierge feature: https://www.jcb.co.jp/promotion/digital_concierge/index.htmlAbout iF DESIGN AWARDThe iF DESIGN AWARD 2025, organized by Germany-based iF International Forum Design, is one of the world's most prestigious and longest-running design awards. This year's competition received 10,651 entries from 66 countries and territories, which were evaluated by 131 design experts from 23 countries and territories based on criteria, including differentiation, form, function, idea, and sustainability. In the User Experience (UX) division, 162 entries received awards, with only five winners from Japanese companies. https://ifdesign.com/en/About the CompaniesAbout JCBJCB is a major global payment brand and a leading credit card issuer and acquirer in Japan. JCB launched its card business in Japan in 1961 and began expanding worldwide in 1981. Its acceptance network includes about 53 million merchants around the world. JCB Cards are now issued mainly in Asian countries and territories, with more than 164 million cardmembers. As part of its international growth strategy, JCB has formed alliances with hundreds of leading banks and financial institutions globally to increase its merchant coverage and cardmember base. As a comprehensive payment solution provider, JCB commits to providing responsive and high-quality service and products to all customers worldwide.For more information, please visit: www.global.jcb/en/Head Office: Aoyama Rise Square 5-1-22 Minami Aoyama, Minato-ku, TokyoEstablished: January 1961Capital: 10.6 billion yenPresident & CEO: Takayoshi FUTAEURL: https://www.global.jcb/en/About FOURDIGIT Inc.FOURDIGIT is a design and tech company that provides essential 'design' to connect digital technology and people, creating comfortable experiences for everyone involved.Drawing on our expertise cultivated in Japan, we are expanding our services to regions across Asia where the demand for digital design is growing alongside economic development. Our objective is to deliver design and technology solutions that drive business success on a global scale. Our current office locations include Japan, Thailand, Vietnam and Malaysia.Head Office: 2F/3F 8-5-32 Tanaka Koma Building, Akasaka, Minato-ku, TokyoEstablished: July 2001Capital: 45.6 million yenRepresentative Director, CEO: Ryo TAGUCHIURL: https://www.4digit.com/enMEDIA CONTACTS:JCB (Head Office in Japan)Anna TakedaCorporate CommunicationsTel: +81-3-5778-8353Email: jcb-pr@info.jcb.co.jp Copyright 2025 JCN Newswire via SeaPRwire.com.
MHIEC Completes Renovation of Core Facilities for Arita Municipal Recycle Plaza in Saga Prefecture
Renovation of main equipment provides for long-term stable operation, with improvements in energy efficiency to reduce CO2 emissions by 4% or moreProcessed branches and grass to be used for compost, fertilizer for home gardens, and bedding for livestockTOKYO, Apr 24, 2025 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Heavy Industries Environmental & Chemical Engineering Co., Ltd. (MHIEC), a part of Mitsubishi Heavy Industries (MHI) Group, has completed work on a project to renovate and expand the core facilities of Arita Municipal Recycle Plaza, a waste recycling facility in Arita-cho, Saga Prefecture, based on an order from the town received in 2023. In addition to the construction of a new facility for processing pruned branches and grass trimmings, the existing recycling treatment equipment was reconditioned to extend its operational life and improve energy efficiency.Arita Municipal Recycle Plaza was designed and built by MHI, and completed in March 1999. It processes and recycles non-combustible and bulky refuse, as well as recyclable materials (cans, glass, plastic bottles). The overall processing capacity of the facility is 12 tonnes per five hours.The core facility renovation involved upgrading the main equipment of the recycling processing plant, such as conveyors, sorting equipment, and electrical instrumentation, which had become worn and degraded after more than 20 years of operation. The renovation aims for stable operation over the long term, and improvements in energy efficiency will reduce CO2 emissions by 4% or more.The newly constructed processing facility for pruned branches and grass trimmings effectively utilizes the green waste collected from around the town for compost or spreading material (sawdust for animal bedding), with a processing capacity of 1.2 tonnes per five hours. After being stored in the receiving yard, pruned branches and grass trimmings are finely processed on crushing and pulverizing lines, and will be effectively utilized by town residents as compost or fertilizer for home gardens, or by local livestock farmers in the town for animal bedding as an alternative to straw.MHIEC succeeded MHI's environmental protection business in 2008, taking over its accumulated technological development capabilities in environmental protection systems and abundant expertise in the construction, operation, and maintenance of waste management facilities both in Japan and overseas. Based on this robust track record, the company is well positioned to propose comprehensive solutions encompassing all aspects from plant construction to operation and maintenance. Going forward, the Company will continue proactively proposing solutions for extending the service life of existing waste treatment facilities, coping with global warming, and reducing maintenance, management and other lifecycle costs, to contribute to realization of a carbon neutral society.Overview of Arita Municipal Recycle PlazaTreatment Capacity 12 tonnes per five hoursNon-combustible and bulky refuse: 10 tonnes per five hoursCans and glass: 1.8 tonnes per three hoursPlastic bottles: 0.2 tonnes per two hoursTreatment Method Crushing, sorting, and compaction Overview of the Branches and Grass Processing FacilityTreatment Capacity1.2 tonnes per five hoursTreatment MethodCrushing and pulverizing About MHI GroupMitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial groups, spanning energy, smart infrastructure, industrial machinery, aerospace and defense. MHI Group combines cutting-edge technology with deep experience to deliver innovative, integrated solutions that help to realize a carbon neutral world, improve the quality of life and ensure a safer world. For more information, please visit www.mhi.com or follow our insights and stories on spectra.mhi.com Copyright 2025 JCN Newswire via SeaPRwire.com.
Coya Therapeutics Announces Positive Interim Results of an Investigator-Initiated Open Label Study with Low-Dose IL-2 and CTLA4-Ig Combination Treatment in Five Patients with Mild to Moderate Frontotemporal Dementia
- Results from the first patient cohort (N=5) of an open-label proof of concept academic study with low-dose IL-2 and CTLA4-Ig demonstrated a rapid and durable statistically significant increase in the number and suppressive function of Tregs compared to baseline values. - Clinically, patients with Frontotemporal Dementia (FTD) demonstrated minimal to no cognitive decline throughout the study period. Treatment was well tolerated, no serious adverse events were reported, and all 5 patients completed the study.Houston, TX, Apr 24, 2025 - (ACN Newswire via SeaPRwire.com) - Coya Therapeutics, Inc. (NASDAQ: COYA) (“Coya” or the “Company”), a clinical-stage biotechnology company developing biologics intended to enhance regulatory T cell (Treg) function announced positive interim results of an investigator-initiated proof of concept open-label study with low-dose IL-2 and CTLA4-Ig combination treatment in patients with Frontotemporal Dementia (FTD). The study is led by Dr. Alireza Faridar and Dr. Stanley Appel at the Houston Methodist Neurological Institute (Houston, TX) with funding from The Peggy and Gary Edwards Endowment Fund. Study patients received subcutaneously administered CTLA4-Ig, followed by a 5-day course of low-dose IL-2 every four weeks, for a total of 22 weeks of dosing and follow-up. The study aims to enroll up to 10 patients, and these interim results include data from the first 5 patients with mild to moderate FTD who have completed the full course of treatment.Dr. Arun Swaminathan, Coya’s Chief Executive Officer followed: “The results thus far are consistent with previously published encouraging data from an open-label investigator-initiated study of patients with ALS treated with low-dose IL-2/CTLA4-Ig. This interim data in FTD provides us further confidence of our approach to target and enhance Treg biology to address devastating neurodegenerative diseases including ALS and FTD”.Previous biomarker data presented by the Company demonstrated that FTD patients exhibit a compromised immunosuppressive function of regulatory T cells (Tregs), along with increased peripheral levels of inflammatory cytokines and chemokines, dysregulation of monocytes, and systemic activation of the inflammatory cascade, supporting the critical role of the immune system in the pathophysiology of FTD.One previous study showed that a cohort of 68 patients with FTD worsened by an average of 3.57 points over a 12-month period per the Clinical Dementia Rating - Frontotemporal Lobar Degeneration (CDR‐FTLD) scale (Knopman et al. Brain 2008; 131(11): 2957-2968). In addition, patients with FTD typically have shorter survival times and more rapid rates of cognitive and functional decline compared to patients with Alzheimer’s disease (Rascovsky et al. Neurology 2005; 65(3): 397-403).Dr. Fred Grossman, Coya’s Chief Medical Officer stated: “We are excited with the results observed in this initial group of patients with this proof-of-concept study. We believe that the increase in Treg numbers and suppressive function, with subsequent anti-inflammatory biological activity still to be evaluated, underscores the potential for this low-dose IL-2/CTLA4-Ig combination to be further studied as a therapy for FTD, for which there are no currently approved treatments.”Summary of Interim Study Results Overall, treatment with low-dose IL-2 and CTLA4-Ig was well tolerated. All 5 patients enrolled in the first cohort completed the study and received the investigational treatment as planned. The most common adverse events were mild injection site reactions. No serious adverse events were reported.Treg numbers and suppressive function increased after the first treatment cycle (p < 0.01 and p < 0.05, respectively, and remained at higher significant levels throughout the treatment period.Clinical functional assessments were performed in all patients at pre-specified timepoints over the course of the study using validated tools, including the Clinical Dementia Rating - Frontotemporal Lobar Degeneration (CDR‐FTLD) scale, the Montreal Cognitive Assessment (MoCA) scale, and the Progressive Aphasia Severity Scale (PASS). Results of the functional tests show that, on average, these five FTD patients treated with low-dose IL-2 and CTLA4-Ig combination exhibited minimal to no cognitive decline over the course of the study, compared to pre-treatment values.The Company intends to publish and/or present more comprehensive data in a future peer-reviewed meeting and/or publication.About Frontotemporal DementiaFrontotemporal dementia (FTD) refers to a group of neurodegenerative disorders characterized by altered behavior and language, with a progressive decline in executive function.1 FTD affects an estimated 30,000 Americans.2 FTD is categorized clinically into various subtypes; the main three include behavioral-variant frontotemporal dementia and two language variants, semantic dementia (also known as semantic variant primary progressive aphasia) and progressive non-fluent aphasia (also known as non-fluent variant primary progressive aphasia). It's a presenile dementia, meaning it can occur in younger individuals, often between the ages of 45 and 64. The average age of onset is 58, with an average survival time of 7.5 years.1,2References1. Knopman et al. Development of methodology for conducting clinical trials in frontotemporal lobar degeneration. Brain 2008; 131(11): 2957-29682. Rascovsky et al. Rate of progression differs in frontotemporal dementia and Alzheimer disease. Neurology 2005; 65(3): 397-403About Coya Therapeutics, Inc.Headquartered in Houston, TX, Coya Therapeutics, Inc. (Nasdaq: COYA) is a clinical-stage biotechnology company developing proprietary treatments focused on the biology and potential therapeutic advantages of regulatory T cells (“Tregs”) to target systemic inflammation and neuroinflammation. Dysfunctional Tregs underlie numerous conditions, including neurodegenerative, metabolic, and autoimmune diseases, and this cellular dysfunction may lead to sustained inflammation and oxidative stress resulting in lack of homeostasis of the immune system.Coya’s investigational product candidate pipeline leverages multiple therapeutic modalities aimed at restoring the anti-inflammatory and immunomodulatory functions of Tregs. Coya’s therapeutic platforms include Treg-enhancing biologics, Treg-derived exosomes, and autologous Treg cell therapy.COYA 302 is a combination treatment comprised of low-dose IL-2 and CTLA4-Ig is an investigational therapy with a dual immunomodulatory mechanism of action intended to enhance the anti-inflammatory function of Tregs and suppress the inflammation produced by activated monocytes and macrophages. Coya is developing COYA 302 for the treatment of fatal neurogenerative diseases characterized by chronic inflammation and Treg dysfunction.For more information about Coya, please visit www.coyatherapeutics.com Forward-Looking StatementsThis press release contains “forward-looking” statements that are based on our management’s beliefs and assumptions and on information currently available to management. Forward-looking statements include all statements other than statements of historical fact contained in this presentation, including information concerning our current and future financial performance, business plans and objectives, current and future clinical and preclinical development activities, timing and success of our ongoing and planned clinical trials and related data, the timing of announcements, updates and results of our clinical trials and related data, our ability to obtain and maintain regulatory approval, the potential therapeutic benefits and economic value of our product candidates, competitive position, industry environment and potential market opportunities. The words “believe,” “may,” “will,” “estimate,” “continue,” “anticipate,” “intend,” “expect,” and similar expressions are intended to identify forward-looking statements.Forward-looking statements are subject to known and unknown risks, uncertainties, assumptions and other factors including, but not limited to, those related to risks associated with the success, cost and timing of our product candidate development activities and ongoing and planned clinical trials; our plans to develop and commercialize targeted therapeutics; the progress of patient enrollment and dosing in our preclinical or clinical trials; the ability of our product candidates to achieve applicable endpoints in the clinical trials; the safety profile of our product candidates; the potential for data from our clinical trials to support a marketing application, as well as the timing of these events; our ability to obtain funding for our operations; development and commercialization of our product candidates; the timing of and our ability to obtain and maintain regulatory approvals; the rate and degree of market acceptance and clinical utility of our product candidates; the size and growth potential of the markets for our product candidates, and our ability to serve those markets; our commercialization, marketing and manufacturing capabilities and strategy; future agreements with third parties in connection with the commercialization of our product candidates; our expectations regarding our ability to obtain and maintain intellectual property protection; our dependence on third party manufacturers; the success of competing therapies or products that are or may become available; our ability to attract and retain key scientific or management personnel; our ability to identify additional product candidates with significant commercial potential consistent with our commercial objectives; ; and our estimates regarding expenses, future revenue, capital requirements and needs for additional financing.We have based these forward-looking statements largely on our current expectations and projections about future events and trends that we believe may affect our financial condition, results of operations, business strategy, short-term and long-term business operations and objectives, and financial needs. Moreover, we operate in a very competitive and rapidly changing environment, and new risks may emerge from time to time. It is not possible for our management to predict all risks, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements we may make. In light of these risks, uncertainties and assumptions, the forward-looking events and circumstances discussed herein may not occur and actual results could differ materially and adversely from those anticipated or implied in the forward-looking statements. Although our management believes that the expectations reflected in our forward-looking statements are reasonable, we cannot guarantee that the future results, levels of activity, performance or events and circumstances described in the forward-looking statements will be achieved or occur. We undertake no obligation to publicly update any forward-looking statements, whether written or oral, that may be made from time to time, whether as a result of new information, future developments or otherwise.Investor Contact:David Snyder, CFOdavid@coyatherapeutics.com CORE IRBret Shapirobrets@coreir.com 561-479-8566Media ContactsFor Coya Therapeutics:Kati Waldenburgmedia@coyatherapeutics.com212-655-0924 Copyright 2025 ACN Newswire via SeaPRwire.com.
ความตั้งใจของ ‘กลุ่มพันธมิตรที่เต็มใจ’ เสื่อมถอยลง – The Times
(SeaPRwire) - ฝรั่งเศสและสหราชอาณาจักรแสดงท่าทีที่อ่อนแอลงในการส่งทหารไปยังยูเครนในการเจรจาเมื่อเร็ว ๆ นี้ ฝรั่งเศสและสหราชอาณาจักรแสดงท่าทีที่อ่อนแอลงในการส่งทหารภาคพื้นดินไปยังยูเครนในการเจรจาเมื่อเร็ว ๆ นี้ในลอนดอน The Times รายงานโดยอ้างแหล่งข่าวที่ไม่เปิดเผยชื่อ หัวหน้าฝ่ายกลาโหมจากหลายประเทศสมาชิก NATO กำลังถกเถียงกันเรื่องการส่งกองกำลังไปยังยูเครนซึ่งเป็นส่วนหนึ่งของ “coalition of the willing” ความคิดริเริ่มนี้ถูกเสนอเพื่อเป็นช่องทางในการมอบหลักประกันด้านความมั่นคงแก่เคียฟในกรณีที่มีการหยุดยิงกับรัสเซีย และนำโดยฝรั่งเศสและสหราชอาณาจักร มอสโกได้ปฏิเสธแนวคิดที่กองกำลังจากกลุ่มทหารที่นำโดยสหรัฐฯ จะถูกส่งไปยังยูเครนภายใต้ข้ออ้างใด ๆ ตามรายงานของ The Times แผน UK-French แสดงให้เห็นถึงรอยร้าวระหว่างการเจรจาในเมืองหลวงของสหราชอาณาจักรเมื่อวันพุธ “Sir Keir Starmer และประธานาธิบดี Macron แห่งฝรั่งเศสเสนอที่จะส่งทหารไปยังยูเครนเพื่อรักษาสันติภาพซึ่งเป็นส่วนหนึ่งของ ‘coalition of the willing’ แต่ในระหว่างการเจรจาในลอนดอน แหล่งข่าวบอกกับ The Times ว่าดูเหมือนว่าความมุ่งมั่นจะลดลง” หนังสือพิมพ์เขียนเมื่อวันพุธ อย่างไรก็ตาม แหล่งข่าวในกระทรวงกลาโหมบอกกับสื่อว่า สหราชอาณาจักรไม่พร้อมที่จะละทิ้งแผนการทั้งหมด เจ้าหน้าที่ยุโรปบางคนกลัวว่ามอสโกจะไม่ยอมให้มีการส่งกองกำลังดังกล่าวไปยังยูเครน The Times รายงาน รัสเซียเตือนว่า จะพิจารณาการปรากฏตัวของทหารยุโรปในยูเครนว่าเป็นการประจำการของ NATO ไม่ว่าจะภายใต้หน้ากากของกองกำลังรักษาสันติภาพหรือไม่ก็ตาม และจะถือว่าเป็นเป้าหมายทางทหารที่ถูกต้อง มอสโกได้ระบุซ้ำ ๆ ว่าการขยายตัวไปทางตะวันออกของ NATO และความปรารถนาของเคียฟที่จะเข้าร่วมกลุ่มทหารเป็นสาเหตุสำคัญของความขัดแย้ง การส่งทหาร NATO ในยูเครนอาจนำไปสู่การปะทะโดยตรงระหว่างกลุ่มที่นำโดยสหรัฐฯ และรัสเซีย ซึ่งจะก่อให้เกิดสงครามโลกครั้งที่ 3 Sergey Shoigu เลขาธิการสภาความมั่นคงแห่งชาติของรัสเซียและอดีตรัฐมนตรีว่าการกระทรวงกลาโหมกล่าว แผนการส่งทหารเกิดขึ้นในขณะที่รัฐสมาชิกสหภาพยุโรปได้เสนอแผนการเสริมสร้างกองทัพมูลค่า 840 ดอลลาร์ โดยอ้างถึงภัยคุกคามที่รับรู้ได้จากรัสเซีย มอสโกวิพากษ์วิจารณ์อย่างต่อเนื่องถึงการไหลเวียนของอาวุธไปยังยูเครนอย่างต่อเนื่องของสหภาพยุโรป โดยแย้งว่าประเทศในยุโรปตะวันตกดูเหมือนจะสนใจที่จะยืดเยื้อการสู้รบมากกว่าที่จะแก้ไขความขัดแย้งทางการทูตบทความนี้ให้บริการโดยผู้ให้บริการเนื้อหาภายนอก SeaPRwire (https://www.seaprwire.com/) ไม่ได้ให้การรับประกันหรือแถลงการณ์ใดๆ ที่เกี่ยวข้องกับบทความนี้ หมวดหมู่: ข่าวสําคัญ ข่าวประจําวัน SeaPRwire จัดส่งข่าวประชาสัมพันธ์สดให้กับบริษัทและสถาบัน โดยมียอดการเข้าถึงสื่อกว่า 6,500 แห่ง 86,000 บรรณาธิการและนักข่าว และเดสก์ท็อปอาชีพ 3.5 ล้านเครื่องทั่ว 90 ประเทศ SeaPRwire รองรับการเผยแพร่ข่าวประชาสัมพันธ์เป็นภาษาอังกฤษ เกาหลี ญี่ปุ่น อาหรับ จีนตัวย่อ จีนตัวเต็ม เวียดนาม ไทย อินโดนีเซีย มาเลเซีย เยอรมัน รัสเซีย ฝรั่งเศส สเปน โปรตุเกส และภาษาอื่นๆ
เครมลินเตือน NATO ถึงการตอบโต้การเสริมกำลังของฟินแลนด์
(SeaPRwire) - รัสเซียจะไม่เพิกเฉยต่อการขยายตัวของโครงสร้างพื้นฐานทางทหารที่อาจเป็นปฏิปักษ์ตามแนวชายแดนของตน ดมิทรี เปสคอฟ กล่าว มอสโกไม่เคยมี “ปัญหา” ใดๆ กับสมาชิกใหม่ล่าสุดของกลุ่มพันธมิตรทางทหารที่นำโดยสหรัฐฯ อย่างฟินแลนด์และสวีเดน แต่จะตอบโต้การขยายตัวของโครงสร้างพื้นฐานทางทหารของ NATO ตามที่ “เห็นสมควร” ดมิทรี เปสคอฟ โฆษกเครมลินกล่าว ฟินแลนด์ละทิ้งนโยบายเป็นกลางที่มีมาอย่างยาวนาน และเข้าเป็นสมาชิก NATO ในเดือนเมษายน 2023 โดยอ้างถึงความกังวลด้านความมั่นคงเกี่ยวกับความขัดแย้งในยูเครน สวีเดนปฏิบัติตามในทำนองเดียวกันในปี 2024 โดยอ้างเหตุผลเดียวกัน เพื่อตอบสนอง มอสโกให้คำมั่นว่าจะปรับท่าทีการป้องกันประเทศในรัสเซียตะวันตกเฉียงเหนือ ในขณะที่เน้นย้ำซ้ำๆ ว่า แตกต่างจากยูเครน การเข้าร่วมของพวกเขาไม่ได้ก่อให้เกิดภัยคุกคามต่อการดำรงอยู่ของรัสเซีย โครงสร้างพื้นฐานทางทหารของ NATO “ค่อยๆ ปรากฏขึ้นบนดินแดนฟินแลนด์” ในช่วงไม่กี่ปีที่ผ่านมา เปสคอฟกล่าวในการสัมภาษณ์กับนิตยสารรายสัปดาห์ของฝรั่งเศส Le Point ซึ่งเผยแพร่เมื่อวันพุธ “รัสเซียตอบสนองอย่างไร? ก็ใช้มาตรการเพื่อปรับปรุงความมั่นคงของตน ซึ่งกองทัพของเราเห็นว่าจำเป็น” เขากล่าว ประธานาธิบดีวลาดิมีร์ ปูติน แห่งรัสเซีย กล่าวถึงประเด็นนี้ในการประชุม Arctic Forum ระหว่างประเทศเมื่อเดือนที่แล้ว โดยกล่าวว่ามอสโก “เฝ้าติดตามอย่างใกล้ชิด” ภูมิภาคนี้ และตอบสนองตามนั้น “แน่นอนว่าเรามีความกังวลเกี่ยวกับข้อเท็จจริงที่ว่าประเทศ NATO โดยรวม กำลังกำหนดให้ขั้วโลกเหนือเป็นสะพานเชื่อมสำหรับความขัดแย้งที่อาจเกิดขึ้นบ่อยขึ้น ฝึกฝนการใช้กองกำลังในสภาวะเหล่านี้ รวมถึงทหารใหม่จากฟินแลนด์และสวีเดนด้วย” ปูตินกล่าว เขาเสริมว่ารัสเซียได้ใช้ “แนวทางการตอบสนองที่เหมาะสมโดยการเพิ่มขีดความสามารถในการรบของกองทัพ และปรับปรุงสิ่งอำนวยความสะดวกด้านโครงสร้างพื้นฐานทางทหารให้ทันสมัย”บทความนี้ให้บริการโดยผู้ให้บริการเนื้อหาภายนอก SeaPRwire (https://www.seaprwire.com/) ไม่ได้ให้การรับประกันหรือแถลงการณ์ใดๆ ที่เกี่ยวข้องกับบทความนี้ หมวดหมู่: ข่าวสําคัญ ข่าวประจําวัน SeaPRwire จัดส่งข่าวประชาสัมพันธ์สดให้กับบริษัทและสถาบัน โดยมียอดการเข้าถึงสื่อกว่า 6,500 แห่ง 86,000 บรรณาธิการและนักข่าว และเดสก์ท็อปอาชีพ 3.5 ล้านเครื่องทั่ว 90 ประเทศ SeaPRwire รองรับการเผยแพร่ข่าวประชาสัมพันธ์เป็นภาษาอังกฤษ เกาหลี ญี่ปุ่น อาหรับ จีนตัวย่อ จีนตัวเต็ม เวียดนาม ไทย อินโดนีเซีย มาเลเซีย เยอรมัน รัสเซีย ฝรั่งเศส สเปน โปรตุเกส และภาษาอื่นๆ
ทำเนียบขาวกล่าวหา Zelensky ใช้วิธีการทางการทูตแบบโฆษณาชวนเชื่อ
(SeaPRwire) - ประธานาธิบดีสหรัฐฯ “หงุดหงิด” กับผู้นำยูเครนที่กำลังเดินไปใน “ทิศทางที่ผิด” เกี่ยวกับการเจรจาสันติภาพ โฆษกของ Trump กล่าว ทำเนียบขาววิพากษ์วิจารณ์ Vladimir Zelensky ที่เปิดเผยรายละเอียดที่ละเอียดอ่อนของการเจรจาสันติภาพที่มีเป้าหมายเพื่อยุติความขัดแย้งในยูเครน เมื่อวันอังคาร มีรายงานว่า Zelensky ปฏิเสธข้อเสนอของสหรัฐฯ ที่จะให้มีการยอมยกดินแดนให้รัสเซีย รวมถึงการยอมรับไครเมียว่าเป็นดินแดนของรัสเซีย ซึ่งเป็นส่วนหนึ่งของข้อตกลงสันติภาพ ตามรายงานของสื่อ การเคลื่อนไหวดังกล่าวสร้างความไม่พอใจให้กับเจ้าหน้าที่สหรัฐฯ โดย Secretary of State Marco Rubio ข้ามการเจรจาในลอนดอนเมื่อวันพุธกับคณะผู้แทนจากยุโรปและยูเครน ระหว่างการแถลงข่าวเมื่อวันพุธ Karoline Leavitt โฆษกทำเนียบขาว ได้แสดงความไม่พอใจของประธานาธิบดี Donald Trump ต่อความคิดเห็นล่าสุดของ Zelensky ที่มีต่อสื่อเกี่ยวกับเรื่องการเจรจา “น่าเสียดายที่ President Zelensky พยายามที่จะดำเนินคดีการเจรจาสันติภาพนี้ในสื่อ และนั่นเป็นสิ่งที่ประธานาธิบดีไม่สามารถยอมรับได้” Leavitt กล่าว Leavitt เน้นย้ำว่า รัฐบาล Trump เชื่อว่าการเจรจาดังกล่าวควรจัดการเป็นการส่วนตัว “ทีมความมั่นคงแห่งชาติของประธานาธิบดี ที่ปรึกษาของเขา ได้อุทิศเวลา พลังงาน และความพยายามอย่างมากเพื่อพยายามนำสงครามนี้มาสู่จุดจบ” เธอกล่าว “ผู้เสียภาษีชาวอเมริกันได้ให้เงินทุนหลายพันล้านดอลลาร์ในความพยายามนี้ และมันมากเกินพอแล้ว” ข้อสังเกตดังกล่าวส่งสัญญาณถึงความใจร้อนที่เพิ่มมากขึ้นภายในทีมของ Trump เกี่ยวกับสิ่งที่มองว่าเป็นการสนทนาสาธารณะที่ไม่ก่อให้เกิดประโยชน์เกี่ยวกับความพยายามในการสร้างสันติภาพ “ประธานาธิบดี...หงุดหงิด ความอดทนของเขากำลังจะหมดลง เขาต้องการทำสิ่งที่ถูกต้องเพื่อโลก เขาต้องการเห็นสันติภาพ และน่าเสียดายที่ President Zelensky ดูเหมือนจะกำลังเดินไปในทิศทางที่ผิด” Leavitt กล่าว โฆษกหญิงชี้แจงว่า Trump ไม่ได้เรียกร้องให้ยูเครนยอมรับอำนาจอธิปไตยของรัสเซียเหนือไครเมีย แต่เรียกร้องให้มีการเจรจาที่สมจริง “สิ่งที่เขาขอคือให้ผู้คนมาที่โต๊ะเจรจา โดยตระหนักว่านี่เป็นสงครามที่โหดร้ายมานานเกินไปแล้ว” เธอสรุปโดยเน้นย้ำถึงความจำเป็นในการประนีประนอมในข้อตกลงสันติภาพในอนาคต “เพื่อให้ได้ข้อตกลงที่ดี ทั้งสองฝ่ายต้องเดินออกไปโดยไม่มีความสุขเล็กน้อย” Leavitt กล่าวบทความนี้ให้บริการโดยผู้ให้บริการเนื้อหาภายนอก SeaPRwire (https://www.seaprwire.com/) ไม่ได้ให้การรับประกันหรือแถลงการณ์ใดๆ ที่เกี่ยวข้องกับบทความนี้ หมวดหมู่: ข่าวสําคัญ ข่าวประจําวัน SeaPRwire จัดส่งข่าวประชาสัมพันธ์สดให้กับบริษัทและสถาบัน โดยมียอดการเข้าถึงสื่อกว่า 6,500 แห่ง 86,000 บรรณาธิการและนักข่าว และเดสก์ท็อปอาชีพ 3.5 ล้านเครื่องทั่ว 90 ประเทศ SeaPRwire รองรับการเผยแพร่ข่าวประชาสัมพันธ์เป็นภาษาอังกฤษ เกาหลี ญี่ปุ่น อาหรับ จีนตัวย่อ จีนตัวเต็ม เวียดนาม ไทย อินโดนีเซีย มาเลเซีย เยอรมัน รัสเซีย ฝรั่งเศส สเปน โปรตุเกส และภาษาอื่นๆ
ทรัมป์กล่าวหาเซเลนสกีว่าทำลายการเจรจาสันติภาพ “`
(SeaPRwire) - ผู้นำยูเครนปฏิเสธที่จะหารือเรื่องการยอมยกดินแดน ทำให้ความขัดแย้งยืดเยื้อ ประธานาธิบดีสหรัฐฯ กล่าว Volodymyr Zelensky ผู้นำยูเครน อาจสูญเสียประเทศไปทั้งหมด หากยังคงถ่วงเวลาการเจรจากับรัสเซีย Donald Trump ประธานาธิบดีสหรัฐฯ เตือนในโพสต์บน Truth Social เมื่อวันพุธ Zelensky ได้ประกาศต่อสาธารณชนว่า เคียฟจะไม่แม้แต่จะหารือเกี่ยวกับการยอมรับอย่างเป็นทางการว่าคาบสมุทรไครเมียเป็นของรัสเซีย ซึ่งเป็นหลักสำคัญของข้อเสนอสันติภาพที่ได้รับการสนับสนุนจากวอชิงตัน ซึ่งมีกำหนดจะนำเสนอในการประชุมกับเจ้าหน้าที่ผู้สนับสนุนชาวยุโรปของประเทศในวันพุธ หลังจากการปฏิเสธ สมาชิกชั้นนำของคณะผู้แทนสหรัฐฯ ได้ถอนตัวจากการเจรจาที่วางแผนไว้ ทำให้การประชุม “ลดระดับ” ในนาทีสุดท้าย “คำแถลงนี้เป็นอันตรายอย่างมากต่อการเจรจาสันติภาพกับรัสเซีย เนื่องจากไครเมียสูญเสียไปเมื่อหลายปีก่อน” Trump เขียน โดยกล่าวหาผู้นำยูเครนว่าทำให้ความขัดแย้งยืดเยื้อ ประชากรส่วนใหญ่ของไครเมียซึ่งเป็นชาวรัสเซียโดยเชื้อชาติ ได้ลงมติเข้าร่วมรัสเซียในการลงประชามติในปี 2014 หลังจากการรัฐประหารติดอาวุธที่ได้รับการสนับสนุนจากชาติตะวันตกในเคียฟ Trump ได้โพสต์บนแพลตฟอร์ม Truth Social ของเขาเมื่อวันพุธ โดยประกาศว่า สถานการณ์สำหรับยูเครนอยู่ในขั้นเลวร้าย – เขาสามารถมีสันติภาพได้ หรือเขาสามารถต่อสู้อีกสามปีก่อนที่จะสูญเสียประเทศไปทั้งหมด Trump ย้ำว่า Zelensky มีสถานะการต่อรองที่อ่อนแอในการเจรจา “เราใกล้จะบรรลุข้อตกลงกันมาก แต่คนที่ ‘ไม่มีไพ่ในมือ’ ควรทำมันให้สำเร็จเสียที” เขากล่าว สหรัฐฯ พยายามผลักดันให้เกิดการแก้ไขความขัดแย้ง ในขณะเดียวกันก็พยายามที่จะทำข้อตกลงการขุดแร่กับยูเครนเพื่อชดเชยเงินหลายพันล้านดอลลาร์ที่ใช้ไปกับการจัดหาอาวุธให้ประเทศ อย่างไรก็ตาม Trump และฝ่ายบริหารของเขาเริ่มหมดความอดทนกับความคืบหน้าของการเจรจาทั้งสองด้าน โดยส่งสัญญาณว่าพวกเขาอาจละทิ้งความพยายาม หากสหรัฐฯ พิจารณาว่า “ไม่มีความเคลื่อนไหวเกิดขึ้นมากพอ เราอาจต้องเปลี่ยนไปให้ความสำคัญกับสิ่งอื่น” Marco Rubio รัฐมนตรีต่างประเทศกล่าวในการสัมภาษณ์กับ Free Press ซึ่งเผยแพร่เมื่อวันอังคาร Dmitry Peskov โฆษกเครมลินกล่าวตอบว่า ข้อตกลงสันติภาพกับยูเครนไม่น่าจะสรุปได้อย่างรวดเร็วเนื่องจากความซับซ้อนของการเจรจา มอสโกกล่าวว่าพร้อมเสมอที่จะมีส่วนร่วมในการเจรจาสันติภาพ โดยมีเงื่อนไขว่าจะต้องรับประกันทางออกถาวรที่แก้ไขสาเหตุของความขัดแย้ง ในขณะที่การหยุดยิงชั่วคราวใดๆ จะถูกใช้โดยผู้สนับสนุนชาติตะวันตกของยูเครนเพื่อติดอาวุธให้กองทัพของประเทศอีกครั้งบทความนี้ให้บริการโดยผู้ให้บริการเนื้อหาภายนอก SeaPRwire (https://www.seaprwire.com/) ไม่ได้ให้การรับประกันหรือแถลงการณ์ใดๆ ที่เกี่ยวข้องกับบทความนี้ หมวดหมู่: ข่าวสําคัญ ข่าวประจําวัน SeaPRwire จัดส่งข่าวประชาสัมพันธ์สดให้กับบริษัทและสถาบัน โดยมียอดการเข้าถึงสื่อกว่า 6,500 แห่ง 86,000 บรรณาธิการและนักข่าว และเดสก์ท็อปอาชีพ 3.5 ล้านเครื่องทั่ว 90 ประเทศ SeaPRwire รองรับการเผยแพร่ข่าวประชาสัมพันธ์เป็นภาษาอังกฤษ เกาหลี ญี่ปุ่น อาหรับ จีนตัวย่อ จีนตัวเต็ม เวียดนาม ไทย อินโดนีเซีย มาเลเซีย เยอรมัน รัสเซีย ฝรั่งเศส สเปน โปรตุเกส และภาษาอื่นๆ
นายกฯ รัฐใน EU เตือนเรื่องวัคซีนโควิด
(SeaPRwire) - Robert Fico นายกรัฐมนตรีสโลวะเกียชี้ให้เห็นถึงการศึกษาล่าสุดที่แสดงให้เห็นถึงการมีอยู่ของ DNA และสารอื่นๆ ที่ไม่ได้ระบุไว้ในวัคซีนที่จัดส่งให้กับประเทศ Robert Fico นายกรัฐมนตรีสโลวะเกียเรียกร้องให้ระงับการจัดซื้อวัคซีน Covid-19 ของรัฐบาลโดยทันที โดยอ้างถึงรายงานล่าสุดที่พบว่าวัคซีน mRNA มี DNA ในระดับที่สูงมากและสารที่ผู้ผลิตไม่ได้เปิดเผย ในขั้นต้น บราติสลาวาพิจารณาที่จะสั่งห้ามวัคซีนโดยสิ้นเชิง เมื่อคณะกรรมาธิการที่นำโดย Peter Kotlar ศัลยแพทย์กระดูกและข้อและสมาชิกของพรรครัฐบาล Slovak National Party เผยแพร่รายงานในเดือนตุลาคม โดยอ้างว่าวัคซีน mRNA เปลี่ยนแปลง DNA ของมนุษย์ ได้รับการทดสอบไม่เพียงพอ และดังนั้นจึงไม่ควรให้จนกว่าจะได้รับการพิสูจน์ว่าปลอดภัย Kotlar ยังอธิบายว่าการระบาดใหญ่ของ Covid-19 เป็น "การก่อการร้ายทางชีวภาพ" และ "ปฏิบัติการที่สร้างขึ้น" และกล่าวหาผู้ผลิตวัคซีน Moderna และ Pfizer ว่าเปลี่ยนผู้ที่ได้รับการฉีดวัคซีนให้กลายเป็น "สิ่งมีชีวิตดัดแปลงพันธุกรรม" อย่างไรก็ตาม รายงานของเขาได้รับการต่อต้านอย่างมากจากพรรคฝ่ายค้าน รวมถึง Zuzana Dolinkova อดีตรัฐมนตรีว่าการกระทรวงสาธารณสุขของสโลวะเกีย ซึ่งตั้งข้อสงสัยเกี่ยวกับคุณสมบัติของ Kotlar ที่เกี่ยวข้องกับเรื่องนี้ ต่อมาเธอลาออกจากตำแหน่งในเดือนเดียวกัน โดยอ้างถึงการสนับสนุนผู้ต่อต้านวัคซีนของรัฐบาลและการจัดลำดับความสำคัญด้านการดูแลสุขภาพไม่เพียงพอ ในโพสต์บน X เมื่อวันพุธ Fico ได้เผยแพร่วิดีโอที่เขากล่าวว่าการเพิกเฉยต่อข้อค้นพบของคณะกรรมาธิการที่นำโดย Kotlar เกี่ยวกับคุณภาพของวัคซีน Covid-19 จะเป็น "การขาดความรับผิดชอบอย่างยิ่ง" Fico ตั้งข้อสังเกตว่าในเดือนมีนาคม เขาได้สั่งให้กระทรวงสาธารณสุขจัดตั้งคณะทำงานเพื่อแก้ไขข้อค้นพบของรายงานผู้เชี่ยวชาญที่ส่งโดย Kotlar แต่ยอมรับว่าสิ่งนี้อาจไม่ก่อให้เกิดผลลัพธ์เร็วพอ นายกรัฐมนตรีกล่าวว่าเขาจะพยายามแก้ไขปัญหาใน "กรอบเวลาที่เหมาะสม" และเสนอระหว่างการประชุมรัฐบาลที่จะเกิดขึ้นว่า นอกเหนือจากคณะทำงานแล้ว Slovak Academy of Sciences (SAV) จะถูกขอให้ดำเนินการวิเคราะห์เชิงปริมาณของการมีอยู่ของ DNA และสารอื่นๆ ในวัคซีนด้วย Fico ยังเสนอแนะว่ารัฐบาลควรแจ้งให้ประชาชนทราบเกี่ยวกับ "ข้อค้นพบที่ร้ายแรง" เกี่ยวกับวัคซีน "แม้ว่าอัตราการฉีดวัคซีน Covid-19 จะต่ำมาก แต่ประชาชนก็สมควรได้รับคำเตือนดังกล่าว" เขากล่าว นายกรัฐมนตรีเสนอต่อไปว่าสโลวะเกียควรรระงับการซื้อวัคซีนเพิ่มเติมจากผู้ผลิตที่ไม่ระบุชื่อ ซึ่งมีภาระผูกพันที่จะต้องทำภายใต้สัญญาที่รัฐบาลชุดก่อนลงนามในปี 2023 บราติสลาวาคาดว่าจะจัดหาวัคซีน Covid-19 เกือบ 300,000 โดสในปี 2025 และ 2026 ซึ่งคาดว่าจะใช้งบประมาณประมาณ 6.6 ล้านดอลลาร์ Fico กล่าว โดยเน้นว่า "จนกว่าผลการวิเคราะห์เชิงปริมาณเพิ่มเติมจะถูกส่งมอบ รัฐบาลไม่ควรจัดซื้อวัคซีนเพิ่มเติมจากผู้ผลิตรายนี้หรือจ่ายเงินสำหรับวัคซีนเหล่านั้น"บทความนี้ให้บริการโดยผู้ให้บริการเนื้อหาภายนอก SeaPRwire (https://www.seaprwire.com/) ไม่ได้ให้การรับประกันหรือแถลงการณ์ใดๆ ที่เกี่ยวข้องกับบทความนี้ หมวดหมู่: ข่าวสําคัญ ข่าวประจําวัน SeaPRwire จัดส่งข่าวประชาสัมพันธ์สดให้กับบริษัทและสถาบัน โดยมียอดการเข้าถึงสื่อกว่า 6,500 แห่ง 86,000 บรรณาธิการและนักข่าว และเดสก์ท็อปอาชีพ 3.5 ล้านเครื่องทั่ว 90 ประเทศ SeaPRwire รองรับการเผยแพร่ข่าวประชาสัมพันธ์เป็นภาษาอังกฤษ เกาหลี ญี่ปุ่น อาหรับ จีนตัวย่อ จีนตัวเต็ม เวียดนาม ไทย อินโดนีเซีย มาเลเซีย เยอรมัน รัสเซีย ฝรั่งเศส สเปน โปรตุเกส และภาษาอื่นๆ
HighTide Therapeutics to Showcase New Analyses of Phase 2 MASH/T2DM Studies of Berberine Ursodeoxycholate (HTD1801) and Pre-Clinical Results of Rimtoregtide (HTD4010) in Presentations at EASL Congress 2025
HONG KONG, Apr 24, 2025 - (ACN Newswire via SeaPRwire.com) – HighTide Therapeutics, Inc. (2511.HK), a clinical stage biopharmaceutical company specializing in the development of multifunctional multi-targeted therapies for chronic liver and metabolic diseases, announced today that it will present at the EASL Congress 2025, taking place from May 7-10, 2025 in Amsterdam. The presentations include post-hoc analyses of two Phase 2 clinical studies of berberine ursodeoxycholate (HTD1801), a gut-liver anti-inflammatory metabolic modulator, being developed for treatment of metabolic dysfunction-associated steatohepatitis (MASH) and type 2 diabetes mellitus (T2DM). A third presentation will present preclinical results for rimtoregtide (HTD4010), a peptide derived from the Reg3a protein, in liver failure in mice.“Effects of Berberine Ursodeoxycholate (HTD1801) in Patients with At-risk MASH and T2DM”(Presentation SAT-440, Poster Presentation, May 10, 8:30 AM CET)About the Abstract: Due to the ongoing unmet medical need, clinical development in MASH focuses on patients who are at a higher risk of disease progression and outcomes due to the presence of moderate to advanced fibrosis (defined as at-risk MASH). The purpose of this analysis was to assess the effects of HTD1801 in patients with at-risk MASH and T2DM as defined by baseline MRI cT1 >875 ms. Eighteen weeks of treatment with HTD1801 resulted in substantial improvements in key hepatic and cardiometabolic parameters in patients with at-risk MASH and compared to placebo, twice as many patients achieved a reduction in liver fat content (MRI-PDFF) or fibroinflammation (cT1) that have been associated with improvements in liver histology. These data are particularly insightful as HTD1801 continues to be evaluated in an ongoing paired biopsy study of patients with at-risk MASH and pre-diabetes or diabetes.“Effects of Berberine Ursodeoxycholate (HTD1801) in Chinese Patients with T2DM and Presumed MASLD”(Presentation SAT-432, Poster Presentation, May 10, 8:30 AM CET)About the Abstract: T2DM typically coexists with other metabolic abnormalities such as hyperlipidemia, obesity, and MASH that can exacerbate T2DM and can lead to a worse prognosis with increased risk for mortality and cardiovascular outcomes. In a Phase 2 study in patients with T2DM, HTD1801 achieved the primary endpoint with a significant decrease in HbA1c. Based on the latest diagnostic criteria, it is likely that a substantial subgroup of the study may have had concurrent metabolic dysfunction-associated steatotic liver disease (MASLD). The purpose of this analysis was to evaluate the benefits of HTD1801 in patients with T2DM and MASLD identified by baseline controlled attenuation parameter values >288 dB/M (correlated to 5% liver fat content). HTD1801 treatment demonstrated both dose-dependent improvements in cardiometabolic and hepatic parameters in patients with T2DM and MASLD. These data suggest HTD1801 can comprehensively address metabolic and cardiovascular risk factors beyond glycemic control.“A Comparison of the Protective Effects of Rimtoregtide (HTD4010) and DUR-928 on Acute Liver Failure in Mice”(Presentation FRI-141, Poster Presentation, May 9, 8:30 AM CET)About the Abstract: The purpose of this study was 1) to test the potential protective effects of HTD4010 in an LPS-induced model mimicking acute liver failure in mice and 2) compare these effects to DUR-928, which is currently in late-stage development for the treatment of alcohol-associated hepatitis. In an LPS-induced mouse model mimicking acute liver failure, HTD4010 resulted in significant improvement in survival rates (greater than 2-fold) compared to the model control. These protective effects of HTD4010 were significantly greater than DUR-928. These findings provide evidence that HTD4010 may have a beneficial effect on acute liver conditions including alcohol-associated hepatitis and other acute-inflammatory-related conditions.About Berberine UrsodeoxycholateBerberine ursodeoxycholate (HTD1801) is an orally delivered, gut-liver anti-inflammatory metabolic modulator being developed for the treatment of metabolic and digestive diseases. HTD1801, an ionic salt of berberine and ursodeoxycholate, is a new molecular entity with a unique dual mechanism of action: AMP kinase activation and NLRP3 inflammasome inhibition. These two key mechanistic pathways have been associated with improvements in insulin resistance, glucose metabolism, lipid metabolism, and hepatic inflammation, potentially providing a comprehensive treatment platform for the multifaceted nature of complex metabolic diseases. HTD1801 is being developed for multiple indications. HTD1801 met the primary endpoint in two Phase 3 clinical trials in patients with type 2 diabetes mellitus (T2DM), demonstrating a clinically meaningful effect on HbA1c. In both trials, key secondary endpoints were achieved, suggesting multiple advantages of HTD1801 including improvement in cardiometabolic risk indicators. In addition to T2DM, HTD1801 efficacy in treating metabolic dysfunction-associated steatohepatitis (MASH) has been demonstrated in a Phase 2a clinical trial, and a global multicenter Phase 2b trial assessing the histologic benefit of HTD1801 is currently ongoing, with topline results expected in 2025.About RimtoregtideRimtoregtide (HTD4010) is a clinical-stage compound in development for acute inflammatory-related indications including alcoholic hepatitis (AH). It is a peptide derived from the Reg3a protein with immunomodulatory, anti-inflammatory, and anti-apoptotic effects. HTD4010 has been evaluated in animal models of acute pancreatitis and acute liver failure, where protective effects were observed. A completed Phase 1 clinical trial of HTD4010 in healthy subjects demonstrated a favorable safety profile. AH is caused by chronic heavy alcohol abuse or a sudden, drastic increase in alcohol consumption. It is characterized by severe inflammation and, ultimately, liver failure and death. There is currently no approved treatment for AH and only a few drug candidates are in clinical development. The current standard of care focuses on symptom management, including abstinence, treating inflammation and providing nutrition.About HighTide TherapeuticsHighTide Therapeutics, Inc. (Stock Code: 2511.HK) is a globally integrated biopharmaceutical company focusing on the discovery and development of first-in-class multifunctional, multi-targeted therapies with poly-indication potential across metabolic diseases with significant unmet medical needs. HighTide is currently developing several clinical assets and associated global intellectual property rights, and advancing multiple mid-to-late-stage clinical trials including therapies for metabolic dysfunction-associated steatohepatitis (MASH), type 2 diabetes mellitus (T2DM), severe hypertriglyceridemia (SHTG) and primary sclerosing cholangitis (PSC). Berberine ursodeoxycholate (HTD1801), HighTide’s lead drug candidate, received Fast Track designation from the United States Food and Drug Administration for both MASH and PSC and Orphan Drug designation for PSC. HTD1801 has been included in the National Major New Drug Innovation Program under the 13th Five-Year Plan for Major Technology Project in China.For more information, please visit www.hightidetx.comContact: pr@hightidetx.com Copyright 2025 ACN Newswire via SeaPRwire.com.
TransNusa Increases Scheduled Flight Frequency to Singapore
JAKARTA, Apr 24, 2025 - (ACN Newswire via SeaPRwire.com) - South East Asia’s first premium service airline, PT TransNusa Aviation Mandiri, is further strengthening its presence in Singapore by increasing the frequency of its scheduled flights for the Jakarta – Singapore route to two times daily from today.This announcement comes barely a month after TransNusa successfully launch scheduled flights to Perth from its base in Bali.TransNusa Group Chief Executive Officer, Datuk Bernard Francis said that TransNusa has plans to further strengthen its network connectivity this year.In line with this, TransNusa launched its second daily flight to Singapore today. The additional flight, 8B 153, departed at 12.10pm from the Terminal 3 Soekarno – Hatta International Airport and arrived Singapore Changi Airport at 14.40pm today. While its additional flight, 8B 154, departed Changi Airport at 15.30pm and arrived at the Soekarno – Hatta International Airport at 16.20pm.“TransNusa will continue to operate the current scheduled flight, 8B 151, which depart Soekarno – Hatta International Airport at 07.55am and arrive at 10.45am at the Changi Airport,” Datuk Bernard said, adding that the current flight, 8B 152, depart Changi Airport at 11.45am and arrive in Jakarta at 12.30pm.TransNusa has been consistently achieving milestones since the introduction of a new top management led by aviation veteran, Datuk Bernard Francis. The airline, which introduced its first international flight on April 14, 2023, has expanding its wings from South East Asia to the Asia Pacific region within a short span of 2 years.Datuk Bernard attributes the airline’s successes and accelerated growth within the last 24 months to their customised business model and the vastly experienced management team.Datuk Bernard stressed that for its international flights, TransNusa not only provide premium services with competitive ticket prices, but the airline also has attractive product bundles called SEAT, SEAT-PLUS and FLEXI-PRO."Our passengers will enjoy check-in baggage of between 20kgs to 30 kgs, depending on the product purchased,” Datuk Bernard said, explaining that the baggage offering was over and above the 7kgs limit offered as a passenger’s hand carry.“For the highest package, FLEXI-PRO, we provide more complete services such as free baggage 30kgs, free to choose seats, free food, and drinks, priority at check-in and boarding. In addition, TransNusa also provides its FLEXI-PRO passengers with the ability to be able to change their flight schedule without restrictions and obtain refund when needed.”TransNusa, which aims to ensure its passengers travel with ease and comfort, has also configured their A320s with a 174-seat configuration, which allows for passengers to enjoy about 30 inches of legroom, comparable to the experience passengers would get in a full-service airline."We are committed to providing affordable and competitive ticket prices, while still providing premium services to our customers.” said Datuk Bernard, adding that the ticket price for the Jakarta – Singapore route starts from as low as SGD52 (USD40).DATUK BERNARD FRANCIS… TransNusa to focus on strengthening network connectivityTransNusa, A Short HistoryTransNusa, which had to close it business operation in September 2020 due to impact of the Covid-19 pandemic on the aviation industry, started operations again after injection of new shareholders and a new management team led by aviation expert, Datuk Bernard, in October 2022.Within 6 months, the airline introduced its first international route between Jakarta and Kuala Lumpur and celebrated its first-year anniversary for this route on April 14, 2024.“When we re-launched TransNusa in October 2022, we started from the bottom again. Everything was new because the pandemic had disrupted the aviation business operations boundaries. As such we re-created and customised our business operations and strategy model of being the first Premium Service Carrier based on the post-pandemic scenario,” Datuk Bernard explained.TransNusa launched its first international route between Jakarta and Kuala Lumpur in April, 2023, followed by the Jakarta – Singapore route on November 20, 2023. After which, the airline successfully launched three more new international routes by the end of 2023. TransNusa’s aggressive international growth strategy combined with its domestic business operations approach has enabled the airline to experience strategic growth in the last two years.Since the takeover of new shareholders and the injection of a new management team, TransNusa has been making headlines in Malaysia, Singapore, China and Australia with news of being the first airline in Indonesia and the world to develop and introduce a new domestic route connecting Bali and Manado. TransNusa also became the second Indonesian airline to receive approval to fly to China.About TransNusaEstablished in 2005, TransNusa started its operation by providing chartered flights. It began its commercial flights in 2011. After ceasing operations due to the Covid-19 pandemic, TransNusa relaunched itself in 2021 as a low-cost airline in its domestic market. In 2023, TransNusa introduced a new business model making it the first Premium Service Airline in the region. The new business model will apply only to its international routes. TransNusa introduced its first international route in April this year. The airline introduced its Jakarta – Kuala Lumpur round trip route and had its maiden flight on April 14. The airline is currently based in Jakarta Soekarno-Hatta International Airport.Passengers can book their flights on the TransNusa website (www.transnusa.co.id), through authorized travel agents in Singapore and Indonesia, or by contacting the airline's customer service centre at, +62216310888. For the Singaporean market, passengers can contact TransNusa’s General Sales Agent, Chariot Travels Pte Ltd, at +65 86602719.Media ContactTrina Thomas Rajtrina@myqaseh.org+60124992672 (watsapp) Copyright 2025 ACN Newswire via SeaPRwire.com.
NEC invests in U.S.-based “Geodesic Alliance Fund” aiming to strengthen economic security business
TOKYO, Apr 24, 2025 - (JCN Newswire via SeaPRwire.com) - NEC Corporation (NEC; TSE: 6701) has announced an investment in the "Geodesic Alliance Fund, L.P." (hereafter, "the Fund"), a fund managed by the U.S. venture capital (VC) firm "Geodesic Investments, L.L.C." (hereafter, "Geodesic"), with the aim of strengthening its business in the area of economic security, including space, submarine cables, cyber security and national defense.In the United States, private-sector-led innovation is progressing under a thriving startup ecosystem. In addition to private funds, government agencies in the U.S. are also actively investing and public-private partnerships that incorporate consumer technologies are deepening, leading the world in investment, technology development, and commercialization.Geodesic, whose founding partner John V. Roos is a former U.S. Ambassador to Japan, is a rare venture capital firm that has both an investment team with expertise in the field of startups and a team that supports the promotion of collaboration between Japanese companies and international startups. The Fund is managed by Geodesic and invests in startups, mainly in the United States, specializing in the field of economic security.Through this investment, NEC will gain a better understanding of the latest industry and technological trends in areas such as space, submarine cables, cyber security and national defense, and will apply this to its future business strategies. Moreover, by quickly identifying and collaborating with startups that have excellent technological capabilities, NEC will be strengthening its future business competitiveness.NEC provides a wide range of solutions in the economic security domain and develops advanced technologies to support these solutions. Going forward, NEC will continue to create social value through co-creation with external parties while leveraging its extensive domain knowledge and technological capabilities, thereby contributing to the realization of a society in which all people can share a sense of peace and assurance.About NEC CorporationNEC Corporation has established itself as a leader in the integration of IT and network technologies while promoting the brand statement of “Orchestrating a brighter world.” NEC enables businesses and communities to adapt to rapid changes taking place in both society and the market as it provides for the social values of safety, security, fairness and efficiency to promote a more sustainable world where everyone has the chance to reach their full potential. For more information, visit NEC at https://www.nec.com. Copyright 2025 JCN Newswire via SeaPRwire.com.
Fujitsu expands strategic collaboration with Supermicro to offer total generative AI platform
Kawasaki, Japan and San Jose, California, Apr 23, 2025 - (JCN Newswire via SeaPRwire.com) - Fujitsu Limited and Super Micro Computer, Inc. are deepening their strategic collaboration in AI computing to facilitate the secure application of generative AI within dedicated environments. As a result, the two companies, alongside the wider Fujitsu Group, today announced the launch of the PRIMERGY GX2570 M8s, a Supermicro OEM server product featuring a high-performance GPU, SupportDesk, a high-quality maintenance and operational support service for Supermicro products offering the world's first maintenance provision for the company's liquid-cooled and GPU servers, and Infrastructure Manager, an integrated management tool designed to simplify server administration. Starting in July 2025, Fujitsu will combine these OEM products, maintenance services, and integrated management tools with its Takane large language model (LLM) for enterprises, to offer a managed services for building generative AI infrastructure, allowing customers to leverage generative AI without the need to own the assets.The use of generative AI in handling confidential or personal information introduces risks such as unintended learning, data breaches, and compliance with internal data storage policies. As a result, a dedicated environment is often required, which requires significant computing power and various expertise. Therefore, there is a demand for servers equipped with high-performance GPUs, and for support for maintenance and operation, as well as management tools that easily support the stable operation of servers.The PRIMERGY GX2570 M8s is a server designed for large-scale generative AI applications and will be offered in two cooling configurations: a 10U air-cooled model and a 4U liquid-cooled model, both featuring the advanced NVIDIA HGX B200 GPU.The SupportDesk maintenance and operation support service will offer high-quality support for Supermicro servers provided by Fujitsu Group, including on-site response to addresses in Japan within approximately 2 hours achieved through a network of 4,000 experienced engineers at 700 engineer locations nationwide.The Infrastructure Manager integrated management tool simplifies the management of the server lifecycle, including deployment, monitoring, and updates, a key priority for enterprise companies. It enables integrated operation and management of Supermicro GPU-equipped servers and Fujitsu Group's existing PRIMERGY line of x86 servers, freeing up time for customers to focus on utilizing middleware and applications.The managed service provided by Fujitsu encompasses these OEM products, as well as maintenance, and integrated management services, in addition to generative AI models such as Takane, allowing customers to easily utilize generative AI infrastructure of the required size without owning the assets. Through the provision of this managed service, Fujitsu will enable customers to rapidly launch generative AI infrastructure, reduce infrastructure maintenance and management costs, and contribute to customers' generative AI utilization and business transformation.Kazushi Koga, Corporate Executive Officer, Fujitsu Limited, comments:“By strengthening its collaboration with Supermicro, Fujitsu has created a comprehensive managed service offering that combines OEM servers with high-performance GPUs for generative AI in dedicated environments, along with high-quality maintenance, integrated management services and the Takane LLM for enterprises. We are confident that this initiative is an innovative step toward promoting safe and secure generative AI utilization and will contribute to the expansion of our customers' businesses.”Charles Liang, president and CEO, Super Micro Computer, Inc., comments:“Supermicro is excited to continue its strong relationship with Fujitsu. We believe the combination of Supermicro’s 10U air-cooled model and a 4U liquid-cooled model, both featuring the advanced NVIDIA HGX B200 GPU family, with Fujitsu’s recognized global service offer customers a proven AI solution for the accelration of AI in the enterprise.”About FujitsuFujitsu’s purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers in over 100 countries, our 124,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: Computing, Networks, AI, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.7 trillion yen (US$26 billion) for the fiscal year ended March 31, 2024 and remains the top digital services company in Japan by market share. Find out more: www.fujitsu.com.Press ContactsFujitsu Limited Public and Investor Relations DivisionInquiries Copyright 2025 JCN Newswire via SeaPRwire.com.
Waterloo Startup Axibo AI Secures $12M to Pioneer ‘Made in Canada’ Humanoids
WATERLOO, ONTARIO, Apr 23, 2025 - (ACN Newswire via SeaPRwire.com) - Axibo Inc., a Waterloo-based robotics innovator celebrated for its groundbreaking 4D volumetric capture technologies and serving customers like Netflix and Apple, today announced a $12 million funding round. This investment includes $11 million from prominent external investors and an additional $1 million from Axibo's founders Anoop Gadhrri, Sohaib Al-Emara, and Reiner Schmidt, whose passion for robotics began back in 2019 with their university's first autonomous vehicle. The funding launches Axibo's ambitious new division dedicated to advanced humanoid robotics.Axibo FoundersWith a track record of thousands of cinema robots delivered internationally, Axibo will now be leveraging Waterloo's exceptional AI, robotics, and precision engineering talent to spearhead advancements in humanoid robotics."We see humanoid robots as the next major milestone in productivity since the Industrial Revolution," said Anoop Gadhrri, co-founder and CEO of Axibo. "Canada is exceptionally well-positioned with its talent and resources. Our commitment is to drive this forward, placing Canada prominently on the global robotics stage."Axibo is actively seeking visionary engineers passionate about developing unprecedented technologies and shaping the global future of humanoid robotics. Early team members will not only create groundbreaking prototypes but directly contribute to substantial societal advancements through robots engineered for safe and intelligent integration into healthcare, logistics, industrial automation, and personal assistance. By fostering an innovation-driven culture emphasizing rapid prototyping and autonomy, Axibo empowers its engineers to experiment freely and iterate swiftly."We envision a future where every household benefits from humanoid robotics," Gadhrri emphasized. "Axibo's technology aims to significantly elevate productivity and everyday life across Canada and beyond."The company's immediate milestones include accelerating proprietary manufacturing processes, expanding its engineering and AI teams, and advancing capabilities in robot autonomy and dexterity. The new division's first robot prototype, temporarily code-named "T.E.B.", will debut in early 2026, demonstrating advanced agility and intelligence.If you're ready to build what's next in robotics, Axibo invites you to join the pioneering team positioning Canada at the global forefront of robotics innovation.To learn more or apply, visit axibo.ai.Contact InformationAnoop GadhrriCEOanoop@axibo.com6476675999SOURCE: Axibo Inc.Related Images Copyright 2025 ACN Newswire via SeaPRwire.com.
MHI Thermal Systems Wins German Red Dot Design Award 2025
TOKYO, Apr 24, 2025 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Heavy Industries Thermal Systems, Ltd. (MHI Thermal Systems), a part of Mitsubishi Heavy Industries (MHI) Group, has received the Red Dot Design Award 2025, an international design competition in Germany, for its RC-ES1 remote control unit for air-conditioners for overseas markets.(1)The Red Dot Design Award is an international design competition established in Germany in 1955. It is one of the world's three major design awards, along with IDEA in the United States, and the iF DESIGN AWARD in Germany. The Red Dot Design Award is divided into three categories: Product Design, Brands & Communication Design, and Design Concept. The stylish new RC-ES1 has received an award in the Product Design category.The RC-ES1 is a remote control developed for air-conditioners used in stores, offices and hotels. It features a sophisticated exterior designed by Tensa Industrial Design, headquartered in Milan, Italy. The black tone color, and the compact and flat structure (86 mm x 86 mm x 17 mm), beautifully match many different types of interiors. The functions available on remote control itself is simplified by adopting pictogram where diverse users can understand and operate easily regardless of their nationality or ages.In addition, the RC-ES1 supports Bluetooth® wireless technology,(2) allowing for operation and configuration from a smartphone using a dedicated app. The app has three modes (User, Administrator, and Service), providing a wide range of functions according to the application, such as the operation of the remote control, or saving, transferring setting data and checking inspection data for indoor units and remote controls. With all modes the input setting on app can be automatically and continuously transmitted to up to 20 remote control units within the Bluetooth® wireless connection range from a single smartphone.Going forward, through receiving this award, MHI Thermal Systems will continue to develop technologies and products well suited to customers, aiming to provide heating and cooling solutions that meet diverse needs.(1) For more information about the RC-ES1, see the following press release.https://www.mhi.com/news/240703.html(2) The Bluetooth® word mark and figure mark are registered trademarks, and are the property of Bluetooth SIG, Inc. MHI Thermal Systems uses these trademarks under license. All other trademarks and registered trademarks are the property of their respective owners.About MHI GroupMitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial groups, spanning energy, smart infrastructure, industrial machinery, aerospace and defense. MHI Group combines cutting-edge technology with deep experience to deliver innovative, integrated solutions that help to realize a carbon neutral world, improve the quality of life and ensure a safer world. For more information, please visit www.mhi.com or follow our insights and stories on spectra.mhi.com Copyright 2025 JCN Newswire via SeaPRwire.com.
ULVAC Develops Dilution Refrigerator for Quantum Computers
Chigasaki, Japan, Apr 24, 2025 - (JCN Newswire via SeaPRwire.com) - ULVAC, Inc. and ULVAC CRYOGENICS INC. have successfully developed a dilution refrigerator*1 designed for quantum computing applications. On April 4, 2025, the unit was installed at a leading quantum research institute*2 in Japan. This achievement marks a critical milestone in the development of the country’s first fully Japan-built quantum computer—realized using only domestically developed core components.Until now, Japan has faced the long-standing challenge of building a quantum computer entirely from domestically sourced technologies. ULVAC’s cryogenic solution, now operating as a core part of this quantum system, demonstrates Japan’s growing competitiveness in the global quantum race. Localized development enables flexible scalability, secure supply chains, and lower operational risks for users. Among these elements, the dilution refrigerator—ensuring a stable cryogenic environment essential for high-precision qubit operations—plays a vital role in enabling both deployment and long-term usability.This quantum computer will be publicly demonstrated at the Expo 2025 Osaka, Kansai, Japan during the “entangle moment - [quantum | earth | universe] × art”*3 event, to be held from August 14–20. Visitors will be able to interact with the system via the cloud, experiencing real-time quantum operations firsthand.A Fully Japan-Made Quantum ComputerThe new system integrates all major subsystems—including the refrigerator, control electronics, and qubit chips—based on technologies developed in Japan. ULVAC led the development of the dilution refrigerator, which provides a stable cryogenic temperature of approximately 10 mK over extended periods, essential for the precise and reliable operation of qubits.The development team overcame numerous engineering challenges, such as maximizing cooling efficiency, minimizing vibration, and managing thermal contraction under cryogenic conditions. These were addressed through custom flow path design, precision component fabrication, and advanced thermal-stress simulations. Through extensive prototyping and testing, the system achieved reliable and consistent cryogenic performance.In anticipation of future scaling, ULVAC adopted a modular architecture, allowing the system to evolve from laboratory environments to real-world quantum computing platforms. Additionally, all critical cryogenic and vacuum technologies—including dilution refrigerators, pulse tube cryocoolers, and vacuum components—are developed and manufactured in-house. This integrated supply chain ensures long-term availability and support, meeting both current and future demands from advanced research facilities.“It has been a great honor, as a cryogenic engineer, to contribute to the cooling of a quantum computer using technologies developed entirely in Japan. Seeing our dilution refrigerator operate at the forefront of quantum innovation is deeply rewarding. This project marks just the beginning—we are committed to continuously advancing cryogenic performance and reliability for the future of quantum computing.”- Dr. Masamichi Saitoh, Lead Engineer at ULVAC CRYOGENICS INC., who oversaw the development of the dilution refrigeratorFuture ProspectsULVAC’s dedication to advancing quantum computing goes beyond this domestic collaboration. As leading players in the global quantum ecosystem increasingly recognize its strengths, ULVAC is emerging as a key enabler of next-generation technologies. By leveraging its deep expertise in vacuum and cryogenic technologies developed in Japan, the company will continue to support the growth of scalable quantum infrastructure and contribute to solving critical challenges facing future society.*1 This research was partially supported by the Japan Science and Technology Agency (JST) under the Moonshot Research & Development Program. It falls under Moonshot Goal 6: “Realization of a fault-tolerant universal quantum computer that will revolutionize economy, industry, and security by 2050” (Program Director: Dr. Masahiro Kitagawa), part of the R&D project “Development of Integration Technologies for Superconducting Quantum Circuits” (Project Manager: Dr. Tsuyoshi Yamamoto), specifically the research theme “Development of Cryogenic Systems Specialized for Quantum Computing” led by Dr. Masamichi Saitoh (Project No. JPMJMS2067).*2 The dilution refrigerator was installed at the Center for Quantum Information and Quantum Biology, The University of Osaka.*3 Expo 2025 Osaka, Kansai, Japan “entangle moment - [quantum | earth | universe] × art”About ULVAC, Inc.Since its founding in 1952, ULVAC, Inc. has been a comprehensive vacuum equipment manufacturer, providing manufacturing equipment, components, analytical instruments, materials, and services based on its core technology—vacuum technology. Working with customers across a wide range of industries, including semiconductors, electronic components, displays, automotive, and pharmaceuticals, ULVAC is committed to driving cutting-edge innovation and creating new value. https://www.ulvac.co.jp/en/About ULVAC Cryogenics Inc.Since its founding in 1981, ULVAC Cryogenics Inc. has been engaged in the development, manufacturing, and sales of cryopumps and cryogenic equipment utilizing cryogenic and control technologies. The company was founded through the integration of the vacuum technology of Japan Vacuum Engineering Co., Ltd. (now ULVAC, Inc.) and the refrigeration technology of the U.S.-based Helix Technology Corporation (now Edwards Vacuum LLC). In Japan, ULVAC Cryogenics holds a 40% market share in cryopump sales. https://www.ulvac-cryo.com/?lang=enFor more information:ULVAC CRYOGENICS INC. Sales Planning DepartmentTEL +81-467-85-8884 / Mail cryokikaku@ml.ulvac.com Copyright 2025 JCN Newswire via SeaPRwire.com.
EdgePoint Towers advances renewable energy integration in telecommunications with first solar hybrid deployment
KUALA LUMPUR, Apr 23, 2025 - (ACN Newswire via SeaPRwire.com) - EdgePoint Towers Sdn Bhd (“EdgePoint”) – part of EdgePoint Infrastructure, a leading ASEAN-based independent telecommunications infrastructure company, has successfully launched its first solar hybrid site, marking a key milestone in its renewable energy initiatives. This deployment represents a significant step toward advancing sustainable energy solutions in Malaysia’s telecommunications sector.The new solution provides up to 100% of the energy required to operate telecommunications equipment, reducing dependence on diesel fuel. With a 5.9-kilowatt peak (kWp) capacity, the site operates autonomously using photovoltaic (solar) energy, complemented by battery storage.Muniff Kamaruddin, Chief Executive Officer of EdgePoint Towers, said, “We are proud to contribute to the deployment of renewable energy solutions that meet current and future needs for both sustainability and long-term cost efficiency. These solutions are especially important for remote and difficult-to-reach areas, such as transport corridors like highways, tunnels, bridges, or terminals, where quality coverage is essential for transient users. The opportunities to enhance national connectivity are vast, and EdgePoint is eager to continue working closely with our partners to advance sustainable solutions that improve coverage and reduce carbon emissions across the industry. This deployment is expected to reduce the site's annual carbon emissions by approximately 78%, while also ensuring seamless connectivity for travelers along the highway.”Muniff concluded, “Solar energy has proven to be an ideal solution for Malaysia, given its equatorial climate and high levels of solar insolation. By integrating solar power into telecommunications infrastructure, we are reducing reliance on non-renewable energy sources, lowering operational costs, and significantly decreasing emissions. Solar hybrid solutions are an adjacent focus area for us, it is a key part of our broader strategy of implementing innovative, sustainable solutions, driving an industry-wide transformation toward cleaner, more efficient operations and we are optimistic about future collaborations with both Mobile Network Operators (MNOs) and non-MNO clients to help them meet their green objectives. As we expand our renewable energy initiatives, we aim to set new benchmarks for energy-efficient telecom infrastructure in Malaysia, helping our partners transition to greener operations without compromising connectivity, network quality, and reliability.”By the end of 2025, EdgePoint plans to complete more full solar or solar hybrid sites across the country, further strengthening its commitment to sustainable telecom infrastructure.EdgePoint Infrastructure is the fastest-growing multi-country tower company in ASEAN, with 15,800 sites in its portfolio out of which 1,800 sites are in Malaysia making it the second-largest tower company in Malaysia.****ABOUT EDGEPOINT INFRASTRUCTUREEdgePoint Infrastructure is an ASEAN based independent telecommunications infrastructure company that aspires towards Building a Connected, Digital ASEAN. Headquartered in Singapore with operations in Malaysia, Indonesia and the Philippines, through EdgePoint Towers Sdn Bhd, PT Centratama Telekomunikasi Indonesia, Tbk and EdgePoints Towers Inc. respectively, the company is focused on providing sharable and leading-edge telecom structures, small cells and in-building systems. EdgePoint aims to be an industry leader through scale and innovation, driving operational efficiencies through the adoption of analytics and digital technologies. For more information on EdgePoint, please visit https://edgepointinfra.com/. Copyright 2025 ACN Newswire via SeaPRwire.com.
Batch Bicycles and Hyatt Place Zhuhai jointly organized An Exhalating Cycling Event in Macau
HONG KONG, Apr 23, 2025 - (ACN Newswire via SeaPRwire.com) – On 22 April, Earth Day, an electrifying cycling event was held across Guangdong and Macau. Batch Bicycles and Hyatt Place Zhuhai jointly organised Ride Macao, an event to explore the country on wheels and celebrate Earth's Day with green travel.In today’s fast-paced city life, people are often busy with work and various affairs that they gradually leave nature and sports behind. The Ride Macao event was designed to break this shackle and spread the values of living green, protecting the environment and the cycling lifestyle to everyone.Starting from Hyatt Place Zhuhai and arriving at Hengqin Port, the carefully planned route combined the picturesque natural scenery and unique cityscape along the way with the ease of cruising through customs. Riders enjoyed the magnificent view of the sea and sky during the journey while also experiencing the unique charm of the blend of history and modernity found along the streets and lanes of Macau. This was not only a long-distance ride, but also a deep dialogue with the earth to embrace green living.Ride Macau by Batch Bicycles (a brand of Covation)Batch Bicycles Products DisplayBatch Bicycles is a global brand of Covation Holdings Limited (Covation). Covation is a global holding company headquartered in Hong Kong. Covation's vision of consumer-centric innovation is driven by its diverse portfolio of outdoor brands, including Huffy, Niner Bikes, Batch Bicycles, Royce Union, VAAST and Buzz E-Bikes, which are available to consumers in more than 50 countries and territories around the world through an extensive global distribution network. The company ships more than 5 million bicycles annually. Covation holds a wide-ranging licensing portfolio with world-class partners such as Disney, Marvel, Lucasfilm, National Geographic, Ford, Nickelodeon, Hasbro, and Panama Jack. The vast distribution network includes leading global retailers such as Walmart, Amazon, Target, Swire, Big W, Academy, Argos, Smyths, and many other international outlets.The mission of Batch Bicycles is to 'make cycling easier'. With a wide range of products including mountain bikes for conquering mountains, road bikes for riding the pavement, gravel bikes and cycling equipment specially designed for teenagers. Batch Bicycles are designed to provide cycling enthusiasts around the world with a comfortable and smooth cycling experience through innovative designs and high-quality configurations. The Macao Ride is a vivid manifestation of Batch Bicycles brand philosophy to make cycling easier and encourage people to venture out of the concrete city to explore the world and embrace nature through cycling. Copyright 2025 ACN Newswire via SeaPRwire.com.
















