เดือน: พฤศจิกายน 2025

TOKYO, Nov 28, 2025 - (JCN Newswire via SeaPRwire.com) - The Japanese Foundation for Cancer Research (JFCR), NEC Corporation (NEC), and Taiho Pharmaceutical Co., Ltd. (Taiho) have signed a three-party joint research (Joint Research) agreement aimed at developing new cancer vaccines through the utilization of whole-genome information.This Joint Research project will be carried out as part of the Japan Agency for Medical Research and Development (AMED)’s "Action Plan for Whole-Genome Analysis for Cancer and Rare/Intractable Diseases," within the research initiative "Demonstration of the Clinical Utility of Cancer Whole-Genome Analysis and Research on Establishing Systems for Patient Benefit."JFCR, NEC, and Taiho will design and develop shared neoantigen cancer vaccines that target newly identified cancer-specific antigens (neoantigens) shared among multiple patients with cancer. The initiative aims to demonstrate the therapeutic efficacy of vaccines for a wide range of cancer patients and to be quickly available.The Joint Research will utilize the unique research information, AI-based drug discovery technologies, and experimental materials held by the three parties. Specifically, JFCR's high quality whole-genome information linked to clinical information*1 for various cancer types with high unmet medical needs*2, common cancer antigens across patients identified with NEC’s proprietary predictive AI technology, and immunological evaluations of the those cancer antigens conducted using Taiho’s proprietary evaluation models, will be used to narrow down highly reliable cancer antigens based on experimental data to design shared neoantigen cancer vaccine candidates suitable for clinical trials. This approach will identify novel cancer-specific antigens shared among multiple patients, including cryptic antigens which are derived from the dark genome*3, in addition to conventional neoantigens, advancing drug discovery research for shared neoantigen cancer vaccines.Cancer vaccines induce immune responses against cancer cells, which differ from conventional chemotherapeutic agents. They hold the potential to become innovative treatments for cancers where unmet medical needs remain. Particularly, there is current expectation for the use of cancer vaccines in preventing postoperative recurrence and early-stage settings*4. Through this Joint Research, the three parties aim to contribute to overcoming the significant social and medical challenges of cancer.Tetsuo Noda, M.D., Ph.D., Advisor, Atsushi Ohtsu, M.D., Ph.D., Research Director at JFCR, stated: "We are delighted to launch this new collaborative initiative with NEC and Taiho to develop novel cancer vaccines by leveraging whole-genome data, under the AMED research program based on the Action Plan for Whole-Genome Analysis 2022 (Ministry of Health, Labour and Welfare). Within this joint research, we will advance the development of shared neoantigen vaccines that integrate both conventional neoantigens and diverse cancer-restricted cryptic antigens derived from the dark genome, identified through AI-driven analysis and immunological validation. Through these efforts, we aspire to realize the next generation of cancer immunotherapy."Motoo Nishihara, Executive Officer, Corporate EVP and CTO at NEC, commented: "We are honored to commence this pioneering collaborative research with JFCR and Taiho to create novel cancer vaccines utilizing whole-genome information. In this Joint Research promoted by AMED, we will combine NEC's proprietary AI-based genome analysis technology with insights into dark genome and neoantigens. This will enable us to address diverse HLA types and achieve highly accurate cancer antigen prediction, which will contribute to creating a future where optimal medical care is delivered to a wider range of patients."Takeshi Sagara, Executive Director, Clinical Development and Medical Affairs, Discovery & Preclinical Research at Taiho, stated: "We believe that future anticancer drug discovery focusing on research and development, not only for advanced cancer, but also for early-stage recurrent cancer, with an eye on the patient journey, will lead to long-term survival and ultimately the overcoming of cancer. We are very pleased to begin this new initiative together with JFCR and NEC toward creating novel cancer vaccines. Utilizing our proprietary patented evaluation models, we will play a key role in evaluating target cancer antigens and identifying clinical trial candidates continuing our challenge in tackling intractable cancers."About the "Comprehensive Genome Analysis Program for Cancer and Intractable Diseases" and the "Research on Verifying the Clinical Utility of Cancer Genome Analysis and Establishing Systems for Patient Benefit"The genome analysis program is a national initiative developed under the Action Plan for Whole-Genome Analysis 2022. It is implemented through collaboration between Practical Research for Innovative Cancer Control and the Practical Research Project for Rare/Intractable Diseases within AMED’s Genome and Data Platform Project. The program aims to achieve future advances in overcoming cancer and rare diseases by strategically accumulating high-quality genomic data and promoting research, drug discovery, and other applications that leverage these data to deliver high-quality healthcare to the public. One of the research groups within this program, titled "Demonstration of the Clinical Utility of Cancer Whole-Genome Analysis and Research on Establishing Systems for Patient Benefit," is conducting studies to evaluate the clinical utility of whole-genome analysis. This research group is also pursuing efforts toward the development of novel therapies, including personalized cancer immunotherapy.*1) Whole-genome information derived from Fresh Frozen-processed tumor tissue and corresponding normal controls (peripheral blood), along with RNA analysis data from the tumor tissue.*2) Refers to unmet medical needs for which no effective treatment currently exists.*3) Regions within the genome sequence whose function or role has not yet been clarified.*4) Zaidi, N., Jaffee, E. M. & Yarchoan, M. Recent advances in therapeutic cancer vaccines. Nature Reviews Cancer, 25, 517–533 (2025). https://doi.org/10.1038/s41568-025-00820-zAbout the Japanese Foundation for Cancer ResearchThe Japanese Foundation for Cancer Research (JFCR) was founded in 1908 as the first organization in Japan specialized for study and control of cancer. JFCR has been playing a leading role in cancer research and treatment for a long time. We have three research centers and a hospital, which are "Cancer Institute" for basic cancer research, "Cancer Chemotherapy Center" for drug development, "Cancer Precision Medicine Center" (CPM Center) and "Cancer Institute Hospital of JFCR" for development of novel cancer treatments. These centers and hospital are working together to achieve our common goal which is cancer control.About NEC CorporationNEC Corporation has established itself as a leader in the integration of IT and network technologies while promoting the brand statement of “Orchestrating a brighter world.” NEC enables businesses and communities to adapt to rapid changes taking place in both society and the market as it provides for the social values of safety, security, fairness and efficiency to promote a more sustainable world where everyone has the chance to reach their full potential. For more information, visit NEC at https://www.nec.com.About Taiho Pharmaceutical Co., Ltd.Taiho Pharmaceutical, a subsidiary of Otsuka Holdings Co., Ltd. (https://www.otsuka.com/en/), is an R&D-driven specialty pharma focusing on the fields of oncology and immune-related diseases. Its corporate philosophy takes the form of a pledge: "We strive to improve human health and contribute to a society enriched by smiles." In the field of oncology, in particular, Taiho Pharmaceutical is known as a leading company in Japan for developing innovative medicines for the treatment of cancer, a reputation that is rapidly expanding through their extensive global R&D efforts. In areas other than oncology, as well, the company creates and markets quality products that effectively treat medical conditions and can help improve people’s quality of life. Always putting customers first, Taiho Pharmaceutical also aims to offer consumer healthcare products that support people’s efforts to lead fulfilling and rewarding lives. For more information about Taiho Pharmaceutical, please visit https://www.taiho.co.jp/en/  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

 TOKYO, Nov 28, 2025 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Heavy Industries, Ltd. (MHI) published its integrated report, "MHI REPORT 2025", which provides a balance of financial and non-financial information of MHI Group and its "SUSTAINABILITY DATABOOK 2025" (the Databook), an annual report summarizing non-financial information of the Group."MHI REPORT 2025" provides explanations centering on our new corporate strategy, Innovative Total Optimization (ITO) established by CEO Eisaku Ito, who took the office in April. In a message from the President and CEO at the beginning, CEO Ito outlines his management approach to achieve Group-Wide Optimization and Reach Expansion to unlock growth potential and establish a virtuous cycle of high profitability and growth investments by creating new value. Next, in a message from the CFO, CFO Hiroshi Nishio shares his perspective on the financial strategy that supports medium- to long-term growth to meet the capital market's expectations of the Group, from perspectives such as financial discipline, resource allocation, and portfolio management.Two feature articles are included. The topic of the first feature is at the forefront of our future growth areas. A message from CSO Masayuki Suematsu explains our growth strategy, centering on the initiatives for growth areas established in the 2024 Medium-Term Business Plan. In a roundtable discussion on the data center business, the feature discusses the future outlook of the market, the Group's strengths, and its eagerness to expand this business. The topic of the second feature is the technology platform supporting MHI Group. In a message from the CTO, CTO Tomoaki Omura shares his own mission to transform our technology platform and lay the groundwork for businesses that can underpin growth in the future, in addition to contributing to the ongoing business operations of the Group. The feature introduces the Shared Technology Framework, which is designed to serve as a Group-wide hub for technology.The latter half of the report contains an article covering a roundtable discussion on the Company's governance system. Three outside directors exchange opinions reflecting on the ten years since the Company transitioned to an Audit and Supervisory Committee structure in 2015. The functions of the Nomination and Remuneration Committee and principles on CEO succession are also covered.The Databook provides the public with information on the progress being achieved by MHI Group in its sustainability management strategy, with content divided into sustainability management, the environment, society, and governance, along with detailed performance data.The 2025 edition of the Databook includes expanded coverage of the Company's initiatives related to the circular economy.(1) Also included are information on the certification of "Wadaoki Forest," a forested area cultivated within Mihara Machinery Works in Hiroshima Prefecture as a "Nationally Certified Sustainably Managed Natural Site" by the Ministry of the Environment, and the "Strategy Map for Well-being and Health Management" developed to promote employee health and well-being.(2)MHI Group aims to contribute to the resolution of the issues facing the world with our diverse technologies, thereby providing value to customers and society while also enhancing our corporate value. Going forward, we will continue to clearly communicate this mission to a broad range of stakeholders.MHI REPORT 2025SUSTAINABILITY DATABOOK 2025(1) A circular economy is an economic system that aims to efficiently circulate resources to promote a sustainable society along with economic growth.(2) Well-being is a concept signifying a state in which individual rights and self-fulfillment are guaranteed, and physical, mental, and social conditions are good.About MHI GroupMitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial groups, spanning energy, smart infrastructure, industrial machinery, aerospace and defense. MHI Group combines cutting-edge technology with deep experience to deliver innovative, integrated solutions that help to realize a carbon neutral world, improve the quality of life and ensure a safer world. For more information, please visit www.mhi.com or follow our insights and stories on spectra.mhi.com  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

Japan, Nov 28, 2025 - (JCN Newswire via SeaPRwire.com) - Sharp has been awarded the "Asia IP Elite 2025" selected by the internationally renowned intellectual property media, Intellectual Asset Management (IAM) for the second consecutive year.Award PlaqueThe Asia IP Elite is an award given by IAM to companies with an intellectual property department and are actively involved in intellectual property transactions and disputes, or that take an innovative approach to extracting value from intellectual property. A total of 101 companies (25 from Japan) have been selected in 2025.Sharp positions its intellectual property strategy as one of its important management strategies, pursuing it together with business and R&D strategies and actively obtaining intellectual property rights. Through such efforts, Sharp is working to enhance its business advantage and enforce its management foundation.To promote this initiative, sharp has been working with Sharp IP Infinity Co., Ltd. which handles intellectual property operations, to strategically create intellectual property value that is closely tied to the field, to create standard essential patents in technological fields such as communications and video, and to strengthen the utilization of intellectual property through international licensing activities.Sharp will continue to proactively pursue intellectual property activities, making use of the knowledge and know-how it has accumulated through its intellectual property activities.About Sharp IP Infinity Co., Ltd.https://sipi.jp.sharp/(Japanese only)  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

KAWASAKI, Japan, Nov 28, 2025 - (JCN Newswire via SeaPRwire.com) - Fujitsu today announced that it has built a platform for NSK Ltd. to support a business model that enables co-creation of value with user companies throughout the product lifecycle of bearing products. This system, which leverages Fujitsu Sustainability Value Accelerator, an offering provided through Fujitsu’s Uvance business model focused on addressing societal challenges, will collect and utilize bearing data across departments, processes, and companies throughout the entire product lifecycle, and provide services for condition monitoring and maintenance. The initiative will promote the reconditioning and reuse of bearing products, supporting NSK's corporate philosophy of contributing to a sustainable society through global environmental conservation, and enhance corporate value.The platform is planned for introduction to bearing product customers as a "Powered by Uvance" product. NSK is currently conducting verification with early adopters and will continuously enhance this system through these trials, aiming for full-scale operation of the platform from 2026. Fujitsu will support NSK in the deployment of this platform, expanding its reach to more users. Furthermore, Fujitsu will continue to promote the circular economy and the generation of new business opportunities through co-creation with NSK, our Uvance Partner. By leveraging reliable data integration, we will realize value co-creation that transcends individual companies and industries, ensuring traceability and environmental value assurance. Figure: Overview of NSK's new business model Comment from Hirofumi Nagai, Head for CMS and PLM Solution Development, Operating Officer, NSK Ltd.:“NSK faced the challenge of developing a new solution from scratch using an agile approach and quickly moving to customer validation. Integrating NSK's proprietary technologies and existing globally deployed condition monitoring solutions also presented significant challenges. By leveraging Fujitsu's solution, we achieved flexible and swift implementation, enabling smooth trial and validation processes. Moving forward, we aim to accelerate initiatives that generate even greater value, such as enhancing decision-making quality through the use of generative AI.”This system integrates and manages data through the bearing product lifecycle for NSK, drawing on Fujitsu's expertise in ensuring traceability within equipment manufacturing supply chains and collecting and managing greenhouse gas (GHG) emissions data, and applies Fujitsu Sustainability Value Accelerator. This will facilitate comprehensive data management for NSK's bearing products, spanning manufacturing to service operations. By integrating NSK's proprietary solutions—including condition monitoring, maintenance optimization, component reconditioning and reuse, and GHG emissions analysis and reduction—Fujitsu will support the co-creation of new value for NSK users throughout the product life and value chain.Fujitsu built this platform using an agile approach on the Sustainability Value Accelerator and launched the initial prototype within three months of development. Following feedback from user companies and NSK's internal teams, functionalities were expanded, achieving rapid operation in a total of six months.Features include:1. Improved equipment utilization rates through integrated bearing management dataThe system integrates and centrally manages design, development, and manufacturing data for bearing products, as well as condition monitoring data from customer’s machines containing bearings, and shares it across NSK departments. Furthermore, by sharing this data with users, it becomes possible to consider and implement prompt countermeasures tailored to the bearing's operating conditions, thereby improving equipment operational efficiency. This enables more efficient utilization of bearings and contributes to reduced environmental impact.2. Adding environmental value to data through blockchain technologyFujitsu will calculate and record environmental value (i.e., GHG reduction amount) based on resource savings achieved through bearing reconditioning as compared to replacement with new bearings. Leveraging the blockchain technology within the Fujitsu Sustainability Value Accelerator offering, the platform manages inspection and maintenance records, along with GHG reduction data, in a tamper-proof manner. By adding reliability to operational bearing product data, GHG reduction quantities can be leveraged as environmental value, enabling users to reuse bearings with greater peace of mind.3. Optimized customer approach through integration with internal and external systemsThis platform acts as a hub for NSK's internal and external systems, enabling seamless data linkage with user companies' existing equipment management systems. By integrating with NSK's customer management system, it supports the optimization of NSK's customer approach, including the development of tailored service menus and proposals for maintenance implementation based on user company conditions.BackgroundNSK is addressing the urgent challenge of climate change by working to reduce GHG emissions throughout the entire product lifecycle—not only within its own manufacturing processes but also extending to the product usage stage by its user companies. As part of this initiative, NSK aims to establish a new business model that co-creates value with user companies across the entire process, from the maintenance and repair of equipment incorporating bearing products to their disposal. To support this, NSK required a platform that could collect and utilize data across its organization to realize various service operations—such as bearing condition monitoring, maintenance, reconditioning (restoring for reuse), and replacement—by integrating NSK's unique product and diagnostic technologies with data from user companies.In response, commissioned by NSK, Fujitsu utilized Fujitsu Sustainability Value Accelerator which ensures traceability of data across companies and industries and supports the realization of a circular economy, to build a platform for the core of NSK's business model.About Powered by Uvance / Uvance PartnerTo achieve the sustainable world envisioned by "Uvance," the presence of partners who bring together diverse knowledge and technologies to co-create the future is essential. These Uvance Partners integrate "Uvance" offerings to develop and provide innovative "Powered by Uvance" products leveraging cutting-edge technologies and expertise. Fujitsu will grow together with Uvance Partners, expanding business and contributing to solving societal challenges.Fujitsu's Commitment to the Sustainable Development Goals (SDGs)The Sustainable Development Goals (SDGs) adopted by the United Nations in 2015 represent a set of common goals to be achieved worldwide by 2030.Fujitsu’s purpose - "to make the world more sustainable by building trust in society through innovation" - is a promise to contribute to the vision of a better future empowered by the SDGs.About FujitsuFujitsu's purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers around the globe, our 113,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: AI, Computing, Networks, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.6 trillion yen (US$23 billion) for the fiscal year ended March 31, 2025 and remains the top digital services company in Japan by market share. Find out more: global.fujitsuPress ContactsFujitsu LimitedPublic and Investor Relations DivisionInquiries  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

KAWASAKI, Japan, Nov 28, 2025 - (JCN Newswire via SeaPRwire.com) - Fujitsu today announced the launch of the Japan Edition of SAP Fioneer Cloud for Insurance, a next-generation platform designed to support core operations in the Japanese insurance industry. Developed in strategic partnership with SAP Fioneer GmbH, the new platform will be available in Japan starting at the end of November, 2025.Built upon SAP Fioneer's globally proven SAP Fioneer Cloud for Insurance [1], the new edition integrates Fujitsu's proprietary functionalities and services tailored to the specific regulatory requirements and business practices of the Japanese insurance market. These all-in-one platform covers a comprehensive range of core insurance operations and systems such as product, policy and claim management. Offered as part of Fujitsu's Uvance initiatives focused on the financial industry, which aim to accelerate digital transformation for financial institutions and contribute to solving societal challenges, the platform will support operational improvements for Japanese insurance companies and drive business transformation across the industry.The platform is enhanced with Fujitsu's unique developments, including functions, templates, and external data linkage capabilities that address specific Japanese market processes and legal regulations. As a first step, the platform will primarily feature common functions and business processes, such as language settings, along with capabilities specifically for automobile insurance, a high-demand area for both agency-based and online insurance.Fujitsu will continue to expand the Japan Edition of SAP Fioneer Cloud for Insurance to support various types of insurance, including automobile insurance. This expansion will drive product, channel, and process transformation, as well as strengthen governance within the Japanese insurance industry.Through the provision of financial industry-focused initiatives with Uvance, Fujitsu will help to enhance the operations of financial institutions and advance the realization of a more prosperous society.Features and benefits of the new editionThe Japan Edition of SAP Fioneer Cloud for Insurance operates on SAP Fioneer Cloud for Insurance and SAP SE's foundational technology, SAP Business Technology Platform.All-in-one platform that enables rapid implementation tailored to unique Japanese insurance market requirements and business customsThis platform offers add-on functionalities, including product templates aligned with Japanese insurance structures, standard business processes from quotation to renewal management, legal compliance, and custom applications, including those for grade-based systems and various surcharges/discounts in automobile insurance.Providing additional add-on functionalities like integrated front-end screens for insurance companies and agencies as well as data creation for external linkage.Improve maintainabilityStandardized functions required by the Japanese insurance industry to minimize the need for individual customization.Local support in Japan offered by Fujitsu to ensure meticulous service delivery.Reduce TCO in non-competitive areasThis platform enables insurance companies to reduce their Total Cost of Ownership (TCO) in non-competitive areas – i.e., business processes that are common across the industry and the systems that support them.Standardization of operations allows insurance companies to reallocate resources towards competitive areas, such as developing new services and enhancing customer experience. Figure: Features offered within the Japan Edition of SAP Fioneer Cloud for InsuranceThe insurance industry is facing dramatic changes in customer needs and the competitive environment, driven by factors such as rapid technological advancement, an aging population and declining birthrate, the emergence of the digital native generation, and the entry of FinTech companies. This necessitates accelerating digital transformation (DX) to address aging systems, IT talent shortages, and governance needs. While adopting global standard core business platform represents one solution, customizing them for the Japanese market remains a major challenge. The Japan Edition of SAP Fioneer Cloud for Insurance was developed in response to these challenges.[1] SAP Fioneer Cloud for Insurance:SAP Fioneer solution that covers end-to-end core insurance business processes, including product management, quoting and underwriting, contract management, insurance payments, and claims collection. It is built on SAP Fioneer’s proven and performant technology and trusted by major insurers around the world.Fujitsu's Commitment to the Sustainable Development Goals (SDGs)The Sustainable Development Goals (SDGs) adopted by the United Nations in 2015 represent a set of common goals to be achieved worldwide by 2030.Fujitsu’s purpose — “to make the world more sustainable by building trust in society through innovation” — is a promise to contribute to the vision of a better future empowered by the SDGs.About FujitsuFujitsu's purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers around the globe, our 113,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: AI, Computing, Networks, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.6 trillion yen (US$23 billion) for the fiscal year ended March 31, 2025 and remains the top digital services company in Japan by market share. Find out more: global.fujitsuPress ContactsFujitsu LimitedPublic and Investor Relations DivisionInquiries  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com